Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India
Joint Authors
Abraham, Asha Mary
John, Kevin
Gunasekaran, Karthik
Prasad, John Davis
Mathew, Divya
Das, Sohini
Sultan, N.
Iyyadurai, Ramya
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We conducted a retrospective observational study to describe the clinical profile and outcomes of patients admitted with a diagnosis of dengue fever in a tertiary hospital in South India.
A total of 159 patients admitted from April 2014 to October 2018 were included in the study.
Vomiting (70.4%), myalgia (60.4%), headache (42.1%), abdominal pain (38.4%), bleeding (38%), and rash (37.1%) were the most common symptoms at presentation.
The mean duration of hospital stay was 4.9 days (SD ± 2.4), and the median cost was INR 19,708 ($285) (IQR INR 12,968–32,056 ($188–$305)).
Major bleeding was associated with elevated SGOT and SGPT, severe dengue, and secondary dengue.
Mortality was associated with elderly age; elevated total leukocyte count, serum bilirubin, serum creatinine, SGOT, and SGPT; and high SOFA score.
In view of these observations, we recommend stratifying patients according to the WHO classification of dengue and avoiding the use of thrombocytopenia as a single marker of the severity of the illness.
American Psychological Association (APA)
John, Kevin& Gunasekaran, Karthik& Prasad, John Davis& Mathew, Divya& Das, Sohini& Sultan, N.…[et al.]. 2019. Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1168767
Modern Language Association (MLA)
John, Kevin…[et al.]. Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India. Interdisciplinary Perspectives on Infectious Diseases No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1168767
American Medical Association (AMA)
John, Kevin& Gunasekaran, Karthik& Prasad, John Davis& Mathew, Divya& Das, Sohini& Sultan, N.…[et al.]. Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India. Interdisciplinary Perspectives on Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1168767
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1168767