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Lignin-Carbohydrate Complexes Based Spherical Biocarriers: Preparation, Characterization, and Biocompatibility
Joint Authors
Zhao, Houkuan
Li, Jinling
Wang, Peng
Zeng, Shaoqiong
Xie, Yimin
Source
International Journal of Polymer Science
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Spherical biocarriers were prepared with lignin-carbohydrate complexes isolated from ginkgo (Ginkgo biloba L.) xylem.
The specific surface and average pore size of the biocarriers were 17.15 m2 g−1 and 21.59 nm, respectively.
The carriers were stable in solution at pH 4.0~9.5.
Fourier transform infrared (FT-IR) spectrum indicated that the spherical carrier was composed of lignin and polysaccharides and had a typical lignin-carbohydrate complex (LCC) structure.
The contents of galactose, lignin, and total sugar were 3.30%, 23.9%, and 64.62%, respectively, making the spherical biocarriers have good physical strength and compatible with hepatocytes.
It was observed using a scanning electron microscopy (SEM) that liver cells adhered to the spherical biocarriers during culture.
Cell counting indicated that the proliferation of liver cells in the experimental group was significantly higher than that of the control group.
The albumin secretion (ALB) value and glucose consumption of the human hepatocytes were increased by 51.7% and 38.6%, respectively, by the fourth day when cultivated on the biocarriers.
The results indicate that ginkgo LCC is very biocompatible and shows promise for the use as a biomaterial in the culture of human hepatocytes.
American Psychological Association (APA)
Zhao, Houkuan& Li, Jinling& Wang, Peng& Zeng, Shaoqiong& Xie, Yimin. 2017. Lignin-Carbohydrate Complexes Based Spherical Biocarriers: Preparation, Characterization, and Biocompatibility. International Journal of Polymer Science،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1169008
Modern Language Association (MLA)
Zhao, Houkuan…[et al.]. Lignin-Carbohydrate Complexes Based Spherical Biocarriers: Preparation, Characterization, and Biocompatibility. International Journal of Polymer Science No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1169008
American Medical Association (AMA)
Zhao, Houkuan& Li, Jinling& Wang, Peng& Zeng, Shaoqiong& Xie, Yimin. Lignin-Carbohydrate Complexes Based Spherical Biocarriers: Preparation, Characterization, and Biocompatibility. International Journal of Polymer Science. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1169008
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169008