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Laser Ablation Electrospray Ionization Time-of-Flight Mass Spectrometry for Direct Analysis of Biological Tissue
Joint Authors
Zhou, Wenzhao
Hong, Yan
Huang, Chaoqun
Shen, Chengyin
Chu, Yannan
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Direct analysis and identification of biological tissue is significant for clinical applications.
In this study, porcine liver and kidney have been analyzed using laser ablation electrospray ionization time-of-flight mass spectrometry (LAESI-TOFMS).
This method showed good reproducibility for the same types of tissue and is capable of distinguishing different tissue species.
The margin assessment was also performed using porcine renal tissue, and the response time was less than 6 s.
Furthermore, human hepatocarcinoma tissue and normal tissue were identified using this method.
Our results indicate that LAESI-TOFMS is a feasible approach for direct identification of tumor tissue and potential for assessment of the resection margin.
American Psychological Association (APA)
Zhou, Wenzhao& Hong, Yan& Huang, Chaoqun& Shen, Chengyin& Chu, Yannan. 2019. Laser Ablation Electrospray Ionization Time-of-Flight Mass Spectrometry for Direct Analysis of Biological Tissue. Journal of Analytical Methods in Chemistry،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1169019
Modern Language Association (MLA)
Zhou, Wenzhao…[et al.]. Laser Ablation Electrospray Ionization Time-of-Flight Mass Spectrometry for Direct Analysis of Biological Tissue. Journal of Analytical Methods in Chemistry No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1169019
American Medical Association (AMA)
Zhou, Wenzhao& Hong, Yan& Huang, Chaoqun& Shen, Chengyin& Chu, Yannan. Laser Ablation Electrospray Ionization Time-of-Flight Mass Spectrometry for Direct Analysis of Biological Tissue. Journal of Analytical Methods in Chemistry. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1169019
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169019