Cytotoxic Phenolic Compounds from Fruit Glandular Trichomes of Macaranga tanarius
Joint Authors
Van Cuong, Pham
Doan, Thi Mai Huong
Nguyen, Thuy Linh
Trinh, Thi Thanh Van
Vu, Van Nam
Phi, Thi Dao
Litaudon, Marc
Roussi, Fanny
Chau, Van Minh
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A new flavonoid, macatanarin D (1), together with five known stilbenes (2-6), was isolated from fruit glandular trichomes of Macaranga tanarius.
Their structures were elucidated on the basis of spectroscopic methods and through comparison with data reported in the literature.
All isolated compounds were evaluated for their cytotoxic activities against KB and MCF-7 cell lines.
Compounds 3, 4, and 5 showed the strongest activities against both cell lines with IC50 values in the range of 0.03–0.12 μM, and compound 2 only showed a significant cytotoxicity against KB cell line (IC50 = 0.26 μM) and a moderate cytotoxicity against MCF-7 (IC50 = 10.4 μM).
Compounds 1 and 6 showed weak cytotoxic activities against KB cell line with IC50 values of 29.3 and 24.7 μM, respectively.
American Psychological Association (APA)
Doan, Thi Mai Huong& Nguyen, Thuy Linh& Trinh, Thi Thanh Van& Vu, Van Nam& Phi, Thi Dao& Litaudon, Marc…[et al.]. 2019. Cytotoxic Phenolic Compounds from Fruit Glandular Trichomes of Macaranga tanarius. Journal of Analytical Methods in Chemistry،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1169095
Modern Language Association (MLA)
Doan, Thi Mai Huong…[et al.]. Cytotoxic Phenolic Compounds from Fruit Glandular Trichomes of Macaranga tanarius. Journal of Analytical Methods in Chemistry No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1169095
American Medical Association (AMA)
Doan, Thi Mai Huong& Nguyen, Thuy Linh& Trinh, Thi Thanh Van& Vu, Van Nam& Phi, Thi Dao& Litaudon, Marc…[et al.]. Cytotoxic Phenolic Compounds from Fruit Glandular Trichomes of Macaranga tanarius. Journal of Analytical Methods in Chemistry. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1169095
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169095
