Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells
Joint Authors
Nyankson, Emmanuel
Asimeng, Bernard Owusu
Efavi, Johnson Kwame
Nii Amarkai, Amartey
Manu, Gloria Pokuaa
Tiburu, Elvis
Source
International Journal of Biomaterials
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Magnetic Fe3O4 nanoparticles were synthesized from maize leaves and plantain peels extract mediators.
Particles were characterized, and the inhibitory effects were studied on HeLa cells in vitro using cyclic voltammetry (CV).
Voltammograms from the CV show that Fe3O4 NPs interaction with HeLa cells affected their electrochemical behavior.
The nanoparticles formed with higher Fe3+/Fe2+ molar ratio (2.8 : 1) resulted in smaller crystallite sizes compared to those formed with lower Fe3+/Fe2+ molar ratio (1.4 : 1).
The particles with the smallest crystallite size showed higher anodic peak currents, whereas the larger crystallite sizes resulted in lower anodic peak currents.
The peak currents relate to cell inhibition and are confirmed by the half-maximum inhibitory concentration (IC50).
The findings show that the particles have a different inhibitory mechanism on HeLa cells ion transfer and are promising to be further exploited for cancer treatment.
American Psychological Association (APA)
Asimeng, Bernard Owusu& Nyankson, Emmanuel& Efavi, Johnson Kwame& Nii Amarkai, Amartey& Manu, Gloria Pokuaa& Tiburu, Elvis. 2020. Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells. International Journal of Biomaterials،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1169196
Modern Language Association (MLA)
Asimeng, Bernard Owusu…[et al.]. Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells. International Journal of Biomaterials No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1169196
American Medical Association (AMA)
Asimeng, Bernard Owusu& Nyankson, Emmanuel& Efavi, Johnson Kwame& Nii Amarkai, Amartey& Manu, Gloria Pokuaa& Tiburu, Elvis. Characterization and Inhibitory Effects of Magnetic Iron Oxide Nanoparticles Synthesized from Plant Extracts on HeLa Cells. International Journal of Biomaterials. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1169196
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169196