Detection of OXA-23 among carbapenem resistant clinical isolates of klebsiella pneumoniae in Hilla
Joint Authors
Jar Allah, Iman Muhammad
Abbas, Fatimah Muin
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 25, Issue 2 (30 Jun. 2017), pp.435-445, 11 p.
Publisher
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Abstract EN
This study aimed to assess the presence of blaOXA-23 in clinical isolates of Klebsiella pneumoniae.
During the period from April to August 2011, a total of 801 various clinical samples were collected from different hospitals in Hilla city.
One hundred and seventy seven (22%) isolates were diagnosed as Klebsiella spp.,117 isolates belonged to K.pneumoniae .
High prevalence of K.pneumoniae was detected in Babylon Teaching Hospital for Maternity and Pediatric with 65 isolates.
Regarding clinical samples, highest rate were observed for stool samples 38 (27%) followed by sputum 19 (15%).
All 117 K.pneumoniae isolates were primarily screened for - lactams resistance, 91 (78%) showed positive results for beta lactams .
β- lactam resistance isolates were underwent antimicrobial susceptibility to 26 antibiotics by Kirby-Bauer disk diffusion methods.
High resistance rate was recorded for penicillins (carbenicillin and ampicillin) 99% and 94.5%,respectively .Carbapenem resistance was reported in 17 (18.7%) of K.
pneumoniae isolates.
The presence of blaOXA-23 gene was checked by Polymerase Chain reaction (PCR) and confirmed in 15 (88.2%) of isolates.
American Psychological Association (APA)
Abbas, Fatimah Muin& Jar Allah, Iman Muhammad. 2017. Detection of OXA-23 among carbapenem resistant clinical isolates of klebsiella pneumoniae in Hilla. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 25, no. 2, pp.435-445.
https://search.emarefa.net/detail/BIM-1169273
Modern Language Association (MLA)
Abbas, Fatimah Muin& Jar Allah, Iman Muhammad. Detection of OXA-23 among carbapenem resistant clinical isolates of klebsiella pneumoniae in Hilla. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 25, no. 2 (2017), pp.435-445.
https://search.emarefa.net/detail/BIM-1169273
American Medical Association (AMA)
Abbas, Fatimah Muin& Jar Allah, Iman Muhammad. Detection of OXA-23 among carbapenem resistant clinical isolates of klebsiella pneumoniae in Hilla. Journal of Babylon University : Journal of Applied and Pure Sciences. 2017. Vol. 25, no. 2, pp.435-445.
https://search.emarefa.net/detail/BIM-1169273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169273