Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis
Joint Authors
Zou, Lu
Lu, Fengyu
Lin, Bing
Zhou, Ying
Liu, Tingting
Sun, Yue
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The drying process of Uncariae Ramulus Cum Uncis (URCU), a kind of traditional Chinese medicine, was studied in a scale dryer in laboratory at 65°C.
It was observed that the alkaloids content of URCU firstly showed a tendency of increasing and then decreasing after reaching the peak at the 570th minute in the process of constant temperature drying.
Moreover, the coagulation time of rabbit determined by test tubes has been adopted to study the effect imposed by the content of alkaloids on the anticoagulating activity of URCU.
In addition, the software of Minitab was also utilized to fit the correlation between the content of alkaloids and the anticoagulating activity of URCU.
The results obtained demonstrated that anticoagulant activities were available in both rhynchophylline and isorhynchophylline, among which the latter was the stronger one, while procoagulant activity was shown in corynoxeine.
The case study can provide a useful reference for the research on drying other Chinese herbal medicines (CHMs) and further study on URCU.
American Psychological Association (APA)
Zou, Lu& Lu, Fengyu& Lin, Bing& Zhou, Ying& Liu, Tingting& Sun, Yue. 2019. Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis. Journal of Analytical Methods in Chemistry،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1169294
Modern Language Association (MLA)
Zou, Lu…[et al.]. Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis. Journal of Analytical Methods in Chemistry No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1169294
American Medical Association (AMA)
Zou, Lu& Lu, Fengyu& Lin, Bing& Zhou, Ying& Liu, Tingting& Sun, Yue. Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis. Journal of Analytical Methods in Chemistry. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1169294
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169294