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Optimization of Extraction Conditions for Determination of Tiliroside in Tilia L. Flowers Using an LC-ESI-MSMS Method
Joint Authors
Pieczykolan, Aleksandra
Pietrzak, Wioleta
Nowak, Renata
Pielczyk, Józefina
Łamacz, Karolina
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Tiliroside exhibits a wide spectrum of effects on the human body; considering expensive synthesis of tiliroside, linden trees seem to be a good source of this compound.
For the first time, 46 various extraction methods were developed to receive tiliroside from Tilia L., including ultrasound-assisted extraction, maceration, maceration with stirring, accelerated solvent extraction, and extraction under reflux.
The effects of extraction techniques, solvents, additives, and temperature on the content of tiliroside were studied using analytical and statistical methods.
A new, rapid, simple, sensitive, and selective liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) method was developed to determine the content of tiliroside in Tilia L.
flowers.
The LC-ESI-MS/MS analysis demonstrated the highest content of tiliroside in Tilia L.
flowers obtained using accelerated solvent extraction (ASE) where 70% ethanol with addition of 1% acetic acid was used as a solvent (7.400 ± 0.019 mg of tiliroside per g dry extract).The results showed that the extracts of Tiliae inflorescentia contained large amounts of tiliroside; therefore, they are good sources of this compound.
Moreover, ASE was found to be superior to other extraction techniques due to its high efficiency as well as considerable saving of time and solvent.
American Psychological Association (APA)
Pieczykolan, Aleksandra& Pietrzak, Wioleta& Nowak, Renata& Pielczyk, Józefina& Łamacz, Karolina. 2019. Optimization of Extraction Conditions for Determination of Tiliroside in Tilia L. Flowers Using an LC-ESI-MSMS Method. Journal of Analytical Methods in Chemistry،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1169355
Modern Language Association (MLA)
Pieczykolan, Aleksandra…[et al.]. Optimization of Extraction Conditions for Determination of Tiliroside in Tilia L. Flowers Using an LC-ESI-MSMS Method. Journal of Analytical Methods in Chemistry No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1169355
American Medical Association (AMA)
Pieczykolan, Aleksandra& Pietrzak, Wioleta& Nowak, Renata& Pielczyk, Józefina& Łamacz, Karolina. Optimization of Extraction Conditions for Determination of Tiliroside in Tilia L. Flowers Using an LC-ESI-MSMS Method. Journal of Analytical Methods in Chemistry. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1169355
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169355