Review of Current Immunologic Therapies for Hidradenitis Suppurativa
Joint Authors
Shanmugam, Victoria K.
Zaman, Nadia Meher
McNish, Sean
Hant, Faye N.
Source
International Journal of Rheumatology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory disease of apocrine gland-bearing skin which affects approximately 1–4% of the population.
The disease is more common in women and patients of African American descent and approximately one-third of patients report a family history.
Obesity and smoking are known risk factors, but associations with other immune disorders, especially inflammatory bowel disease, are also recognized.
The pathogenesis of HS is poorly understood and host innate or adaptive immune response, defective keratinocyte function, and the microbial environment in the hair follicle and apocrine gland have all been postulated to play a role in disease activity.
While surgical interventions can be helpful to reduce disease burden, there is a high recurrence rate.
Increasingly, data supports targeted immune therapy for HS, and longitudinal studies suggest benefit from these agents, both when used alone and as an adjunct to surgical treatments.
The purpose of this review is to outline the current data supporting use of targeted immune therapy in HS management.
American Psychological Association (APA)
Shanmugam, Victoria K.& Zaman, Nadia Meher& McNish, Sean& Hant, Faye N.. 2017. Review of Current Immunologic Therapies for Hidradenitis Suppurativa. International Journal of Rheumatology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1169384
Modern Language Association (MLA)
Shanmugam, Victoria K.…[et al.]. Review of Current Immunologic Therapies for Hidradenitis Suppurativa. International Journal of Rheumatology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1169384
American Medical Association (AMA)
Shanmugam, Victoria K.& Zaman, Nadia Meher& McNish, Sean& Hant, Faye N.. Review of Current Immunologic Therapies for Hidradenitis Suppurativa. International Journal of Rheumatology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1169384
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169384