Postmastectomy Radiation Therapy: Are We Ready to Individualize Radiation?
Joint Authors
De Los Santos, Jennifer
Everett, Ashlyn S.
Boggs, Drexell Hunter
Source
International Journal of Breast Cancer
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Contemporary recommendations for postmastectomy radiation have undergone a shift in thinking away from simple stage based recommendations (one size fits all) to a system that considers both tumor biology and host factors.
While surgical staging has traditionally dictated indications for postmastectomy radiation therapy (PMRT), our current understanding of tumor biology, host, immunoprofiles, and tumor microenvironment may direct a more personalized approach to radiation.
Understanding the interaction of these variables may permit individualization of adjuvant therapy aimed at appropriate escalation and deescalation, including recommendations for PMRT.
This article summarizes the current data regarding tumor and host molecular biomarkers in vitro and in vivo that support the individualization of PMRT and discusses open questions that may alter the future of breast cancer treatment.
American Psychological Association (APA)
Everett, Ashlyn S.& Boggs, Drexell Hunter& De Los Santos, Jennifer. 2018. Postmastectomy Radiation Therapy: Are We Ready to Individualize Radiation?. International Journal of Breast Cancer،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1169417
Modern Language Association (MLA)
Everett, Ashlyn S.…[et al.]. Postmastectomy Radiation Therapy: Are We Ready to Individualize Radiation?. International Journal of Breast Cancer No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1169417
American Medical Association (AMA)
Everett, Ashlyn S.& Boggs, Drexell Hunter& De Los Santos, Jennifer. Postmastectomy Radiation Therapy: Are We Ready to Individualize Radiation?. International Journal of Breast Cancer. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1169417
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169417