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Strain and Vibration in Mesenchymal Stem Cells
Joint Authors
McClarren, Brooke
Olabisi, Ronke M.
Source
International Journal of Biomaterials
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-09
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into any mesenchymal tissue, including bone, cartilage, muscle, and fat.
MSC differentiation can be influenced by a variety of stimuli, including environmental and mechanical stimulation, scaffold physical properties, or applied loads.
Numerous studies have evaluated the effects of vibration or cyclic tensile strain on MSCs towards developing a mechanically based method of differentiation, but there is no consensus between studies and each investigation uses different culture conditions, which also influence MSC fate.
Here we present an overview of the response of MSCs to vibration and cyclic tension, focusing on the effect of various culture conditions and strain or vibration parameters.
Our review reveals that scaffold type (e.g., natural versus synthetic; 2D versus 3D) can influence cell response to vibration and strain to the same degree as loading parameters.
Hence, in the efforts to use mechanical loading as a reliable method to differentiate cells, scaffold selection is as important as method of loading.
American Psychological Association (APA)
McClarren, Brooke& Olabisi, Ronke M.. 2018. Strain and Vibration in Mesenchymal Stem Cells. International Journal of Biomaterials،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1169631
Modern Language Association (MLA)
McClarren, Brooke& Olabisi, Ronke M.. Strain and Vibration in Mesenchymal Stem Cells. International Journal of Biomaterials No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1169631
American Medical Association (AMA)
McClarren, Brooke& Olabisi, Ronke M.. Strain and Vibration in Mesenchymal Stem Cells. International Journal of Biomaterials. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1169631
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169631