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Outcomes and Recommendations of an Indian Expert Panel for Improved Practice in Controlled Ovarian Stimulation for Assisted Reproductive Technology
Joint Authors
Ahemmed, Baiju
Sundarapandian, Vani
Gutgutia, Rohit
Balasubramanyam, Sathya
Jagtap, Richa
Biliangady, Reeta
Gupta, Priti
Jadhav, Sachin
Satwik, Ruma
Dewda, Pavitra Raj
Thakor, Priti
Esteves, Sandro C.
Source
International Journal of Reproductive Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Purpose.
To improve success of in vitro fertilization (IVF), assisted reproductive technology (ART) experts addressed four questions.
What is optimum oocytes number leading to highest live birth rate (LBR)? Are cohort size and embryo quality correlated? Does gonadotropin type affect oocyte yield? Should “freeze-all” policy be adopted in cycles with progesterone >1.5 ng/mL on day of human chorionic gonadotropin (hCG) administration? Methods.
Electronic database search included ten studies on which panel gave opinions for improving current practice in controlled ovarian stimulation for ART.
Results.
Strong association existed between retrieved oocytes number (RON) and LBRs.
RON impacted likelihood of ovarian hyperstimulation syndrome (OHSS).
Embryo euploidy decreased with age, not with cohort size.
Progesterone > 1.5 ng/dL did not impair cycle outcomes in patients with high cohorts and showed disparate results on day of hCG administration.
Conclusions.
Ovarian stimulation should be designed to retrieve 10–15 oocytes/treatment.
Accurate dosage, gonadotropin type, should be selected as per prediction markers of ovarian response.
Gonadotropin-releasing hormone (GnRH) antagonist based protocols are advised to avoid OHSS.
Cumulative pregnancy rate was most relevant pregnancy endpoint in ART.
Cycles with serum progesterone ≥1.5 ng/dL on day of hCG administration should not adopt “freeze-all” policy.
Further research is needed due to lack of data availability on progesterone threshold or index.
American Psychological Association (APA)
Ahemmed, Baiju& Sundarapandian, Vani& Gutgutia, Rohit& Balasubramanyam, Sathya& Jagtap, Richa& Biliangady, Reeta…[et al.]. 2017. Outcomes and Recommendations of an Indian Expert Panel for Improved Practice in Controlled Ovarian Stimulation for Assisted Reproductive Technology. International Journal of Reproductive Medicine،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1169683
Modern Language Association (MLA)
Ahemmed, Baiju…[et al.]. Outcomes and Recommendations of an Indian Expert Panel for Improved Practice in Controlled Ovarian Stimulation for Assisted Reproductive Technology. International Journal of Reproductive Medicine No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1169683
American Medical Association (AMA)
Ahemmed, Baiju& Sundarapandian, Vani& Gutgutia, Rohit& Balasubramanyam, Sathya& Jagtap, Richa& Biliangady, Reeta…[et al.]. Outcomes and Recommendations of an Indian Expert Panel for Improved Practice in Controlled Ovarian Stimulation for Assisted Reproductive Technology. International Journal of Reproductive Medicine. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1169683
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169683