Management Options for Advanced Low or Intermediate Grade Gastroenteropancreatic Neuroendocrine Tumors: Review of Recent Literature
Joint Authors
Neychev, Vladimir
Kebebew, Electron
Source
International Journal of Surgical Oncology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-16
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Our understanding of the biology, genetics, and natural history of neuroendocrine tumors (NETs) of the gastrointestinal tract and pancreas has improved considerably in the last several decades and the spectrum of available therapeutic options is rapidly expanding.
The management of patients with metastatic low or intermediate grade NETs has been revolutionized by the development of new treatment strategies such as molecular targeting therapies with everolimus and sunitinib, somatostatin analogs, tryptophan hydroxylase inhibitors, and peptide receptor radionuclide therapy that can be used alone or as a multimodal approach with or without surgery.
To further define and clarify the utility, appropriateness, and the sequence of the growing list of available therapies for this patient population will require more high level evidence; however, data from well-designed randomized phase III clinical trials is rapidly accumulating that will further stimulate development of new management strategies.
It is therefore important to thoroughly review emerging evidence and report major findings in frequent updates, which will expand our knowledge and contribute to a better understanding, characterization, and management of advanced NETs.
American Psychological Association (APA)
Neychev, Vladimir& Kebebew, Electron. 2017. Management Options for Advanced Low or Intermediate Grade Gastroenteropancreatic Neuroendocrine Tumors: Review of Recent Literature. International Journal of Surgical Oncology،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1169709
Modern Language Association (MLA)
Neychev, Vladimir& Kebebew, Electron. Management Options for Advanced Low or Intermediate Grade Gastroenteropancreatic Neuroendocrine Tumors: Review of Recent Literature. International Journal of Surgical Oncology No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1169709
American Medical Association (AMA)
Neychev, Vladimir& Kebebew, Electron. Management Options for Advanced Low or Intermediate Grade Gastroenteropancreatic Neuroendocrine Tumors: Review of Recent Literature. International Journal of Surgical Oncology. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1169709
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1169709