Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules
Joint Authors
Zhang, Shui-xing
Pei, Shufang
Zhang, Bin
Cong, Shuzhen
Liu, Juanjuan
Wu, Suqing
Dong, Yuhao
Zhang, Lu
Source
International Journal of Endocrinology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
To explore the correlation between the ultrasound elasticity score (ES) of real-time tissue elastography (RTE) and the malignant risk stratification of the Thyroid Imaging Reporting and Data System (TI-RADS) and to evaluate the added value of RTE to TI-RADS in differentiating malignant nodules from benign ones.
Methods.
A total of 1,498 patients (885 women and 613 men; mean age of 43.5 ± 12.4 years) with 1,525 confirmed thyroid nodules (D = maximum diameter, D ≤ 2.5 cm) confirmed by fine-needle aspiration (FNA) and/or surgery were included.
The nodules were divided into four groups based on their sizes (D ≤ 0.5 cm, 0.5 < D ≤ 1.0 cm, 1.0 < D ≤ 2.0 cm, and 2.0 < D ≤ 2.5 cm).
We assigned an ES of RTE and malignant risk stratification of the TI-RADS category to each nodule.
The correlation between the ES of RTE and the malignant risk stratification of TI-RADS category was analyzed by the Spearman’s rank correlation.
The diagnostic performances of RTE, TI-RADS, and their combination were compared by the receiver operator characteristic (ROC) analysis.
Results.
The ES of RTE and the malignant risk stratification of TI-RADS showed a strong correlation in the size intervals of 0.5 < D ≤ 1.0 cm, 1.0 < D ≤ 2.0 cm, and 2.0 < D ≤ 2.5 cm (r = 0.768, 0.711, and 0.743, respectively).
The diagnostic performance of their combination for each size interval was always better than RTE or TI-RADS alone (for all, P<0.001).
Conclusions.
Overall, The ES of RTE was strongly correlated with the malignant risk stratification of TI-RADS.
The diagnostic performance of the combination of RTE and TI-RADS outperformed RTE or TI-RADS alone.
Therefore, RTE may be an adjunctive tool to the current TI-RADS system for differentiating malignant from benign thyroid nodules.
American Psychological Association (APA)
Pei, Shufang& Zhang, Bin& Cong, Shuzhen& Liu, Juanjuan& Wu, Suqing& Dong, Yuhao…[et al.]. 2020. Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules. International Journal of Endocrinology،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1170106
Modern Language Association (MLA)
Pei, Shufang…[et al.]. Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules. International Journal of Endocrinology No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1170106
American Medical Association (AMA)
Pei, Shufang& Zhang, Bin& Cong, Shuzhen& Liu, Juanjuan& Wu, Suqing& Dong, Yuhao…[et al.]. Ultrasound Real-Time Tissue Elastography Improves the Diagnostic Performance of the ACR Thyroid Imaging Reporting and Data System in Differentiating Malignant from Benign Thyroid Nodules: A Summary of 1525 Thyroid Nodules. International Journal of Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1170106
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170106