Simultaneous Determination of 5 Flavonoids and 7 Saponins for Quality Control of Traditional Chinese Medicine Preparation Xinnaoshutong Capsule Using HPLC-VWD-ELSD
Joint Authors
Hu, Limin
Chang, Yanxu
Gao, Xiu-Mei
Li, Jin
He, Jun
Cao, Jun
An, Mingrui
Bai, Yang
Zhang, Peng
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Xinnaoshutong capsule (XC) is a traditional Chinese prescription derived from the ripe fruit of Tribulus terrestris L.
(TT).
Although XC has long been considered as an important herbal medicine, no analytical method of marker compounds for quality assessment is registered in the Chinese Pharmacopoeia.
A simple analytical method of twelve marker components was developed and validated by HPLC-VWD-ELSD method.
Chromatographic separation by HPLC was carried out on a Hedera ODS 2 column (4.6 × 250 mm, 5 μm) by gradient elution with acetonitrile-water (0.1% formic acid) as the mobile phase.
Various extraction conditions were optimized to achieve twelve marker compounds with faster extraction and higher recovery.
The analytical condition was then validated in terms of the linearity, accuracy and precision, repeatability, and stability.
The twelve markers were successfully quantified in 30 batches of commercial samples.
The developed HPLC-VWD-ELSD could be used as a rapid and reliable way in the assessment and quality control of XC and TT.
American Psychological Association (APA)
Li, Jin& Bai, Yang& Zhang, Peng& He, Jun& Cao, Jun& An, Mingrui…[et al.]. 2017. Simultaneous Determination of 5 Flavonoids and 7 Saponins for Quality Control of Traditional Chinese Medicine Preparation Xinnaoshutong Capsule Using HPLC-VWD-ELSD. Journal of Analytical Methods in Chemistry،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1170151
Modern Language Association (MLA)
Li, Jin…[et al.]. Simultaneous Determination of 5 Flavonoids and 7 Saponins for Quality Control of Traditional Chinese Medicine Preparation Xinnaoshutong Capsule Using HPLC-VWD-ELSD. Journal of Analytical Methods in Chemistry No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1170151
American Medical Association (AMA)
Li, Jin& Bai, Yang& Zhang, Peng& He, Jun& Cao, Jun& An, Mingrui…[et al.]. Simultaneous Determination of 5 Flavonoids and 7 Saponins for Quality Control of Traditional Chinese Medicine Preparation Xinnaoshutong Capsule Using HPLC-VWD-ELSD. Journal of Analytical Methods in Chemistry. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1170151
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170151