The Number of Central Lymph Nodes on Preoperative Ultrasound Predicts Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Cohort Study
Joint Authors
Gao, Luying
Wang, Juanjuan
Jiang, Yuxin
Gao, Qiong
Wang, Ying
Xi, Xuehua
Zhang, Bo
Source
International Journal of Endocrinology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
To evaluate the effectiveness of the number of central compartment lymph nodes (CLNs) on ultrasound (US) in predicting CLN metastasis (CLNM).
We prospectively studied 309 papillary thyroid cancer (PTC) patients who underwent thyroidectomy with CLN dissection at our center from May 2017 to July 2017.
The number and features of CLNs were evaluated preoperatively via US.
All US examinations were performed using a Philips iU 22 or a GE Logiq 9 machine.
Correlations between CLNs observed via preoperative US and amount of CLNM were evaluated.
We found that ≥2 CLNs on the preoperative US was associated with CLNM (P<0.01).
For this feature, the sensitivity, specificity, and area under the curve (AUC) were 54.3%, 66.1%, and 0.61, respectively.
The presence of both suspected metastasis and ≥2 CLNs on US had a specificity of 86.5%.
In addition, ≥3 CLNs on preoperative US was associated with large-volume CLNM (>5 metastatic CLNs) (P<0.01).
For this feature, the sensitivity, specificity and AUC were 54.8%, 74.5% and 0.65, respectively.
The presence of both suspected metastasis and ≥3 CLNs on US had a specificity of 84.9%.
The presence of suspected metastasis and/or ≥3 CLNs had a sensitivity of 80.6%.
Our results suggest that ≥2 and ≥ 3 CLNs on preoperative US may serve as ancillary preoperative markers for predicting CLNM.
American Psychological Association (APA)
Gao, Luying& Wang, Juanjuan& Jiang, Yuxin& Gao, Qiong& Wang, Ying& Xi, Xuehua…[et al.]. 2020. The Number of Central Lymph Nodes on Preoperative Ultrasound Predicts Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Cohort Study. International Journal of Endocrinology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1170177
Modern Language Association (MLA)
Gao, Luying…[et al.]. The Number of Central Lymph Nodes on Preoperative Ultrasound Predicts Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Cohort Study. International Journal of Endocrinology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1170177
American Medical Association (AMA)
Gao, Luying& Wang, Juanjuan& Jiang, Yuxin& Gao, Qiong& Wang, Ying& Xi, Xuehua…[et al.]. The Number of Central Lymph Nodes on Preoperative Ultrasound Predicts Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Prospective Cohort Study. International Journal of Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1170177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170177