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Structural and Quantitative Analysis of Three C-Glycosylflavones by Variable Temperature Proton Quantitative Nuclear Magnetic Resonance
Joint Authors
Ma, Shuang-Cheng
Dai, Zhong
Liu, Yang
He, Lan
Liu, Jing
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Quantitative nuclear magnetic resonance is a powerful tool in drug analysis because of its speed, precision, and efficiency.
In present study, the application of variable temperature proton quantitative nuclear magnetic resonance (VT-1H-qNMR) for the calibration of three C-glycosylflavones including orientin, isoorientin, and schaftoside as reference substances was reported.
Since there was conformational equilibrium due to the restricted rotation around the C(sp3)-C(sp2) bond in C-glycosylflavones, the conformational behaviors were investigated by VT-NMR and verified by molecular mechanics (MM) calculation.
The VT-1H-qNMR method was validated including the linearity, limit of quantification, precision, and stability.
The results were consistent with those obtained from mass balance approach.
VT-1H-qNMR can be deployed as an effective tool in analyzing C-glycosylflavones.
American Psychological Association (APA)
Liu, Jing& Liu, Yang& Dai, Zhong& He, Lan& Ma, Shuang-Cheng. 2017. Structural and Quantitative Analysis of Three C-Glycosylflavones by Variable Temperature Proton Quantitative Nuclear Magnetic Resonance. Journal of Analytical Methods in Chemistry،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1170220
Modern Language Association (MLA)
Liu, Jing…[et al.]. Structural and Quantitative Analysis of Three C-Glycosylflavones by Variable Temperature Proton Quantitative Nuclear Magnetic Resonance. Journal of Analytical Methods in Chemistry No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1170220
American Medical Association (AMA)
Liu, Jing& Liu, Yang& Dai, Zhong& He, Lan& Ma, Shuang-Cheng. Structural and Quantitative Analysis of Three C-Glycosylflavones by Variable Temperature Proton Quantitative Nuclear Magnetic Resonance. Journal of Analytical Methods in Chemistry. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1170220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170220