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Quality of Ceftriaxone Sodium in Lyophilized Powder for Injection Evaluated by Clean, Fast, and Efficient Spectrophotometric Method
Joint Authors
Salgado, Hérida Regina Nunes
Kogawa, Ana Carolina
de Aléssio, Patrícia Vidal
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-05
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Ceftriaxone sodium, an antimicrobial agent that plays an important role in clinical practice, is successfully used to treat infections caused by most Gram-positive and Gram-negative organisms.
Since there are few rapid analytical methods for ceftriaxone analysis to use in the pharmaceutical routine, the aim of this research was to develop a new method able to quantify this cephalosporin.
Therefore, a sensitive, rapid, simple UV spectrophotometric method for the determination and quantification of ceftriaxone sodium was proposed.
The UV detector was set at 241 nm.
Beer’s law obeyed the concentration range of 10–20 µg mL−1.
Statistical comparison of the results with a well-established reported method showed excellent agreement and proved that there is no significant difference in the accuracy and precision.
Intra- and interday variability for the method were less than 2% relative standard deviation.
The proposed method was applied to the determination of the examined drugs in pharmaceutical formulations and the results demonstrated that the method is equally accurate, precise, and reproducible as the official methods.
American Psychological Association (APA)
de Aléssio, Patrícia Vidal& Kogawa, Ana Carolina& Salgado, Hérida Regina Nunes. 2017. Quality of Ceftriaxone Sodium in Lyophilized Powder for Injection Evaluated by Clean, Fast, and Efficient Spectrophotometric Method. Journal of Analytical Methods in Chemistry،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1170300
Modern Language Association (MLA)
de Aléssio, Patrícia Vidal…[et al.]. Quality of Ceftriaxone Sodium in Lyophilized Powder for Injection Evaluated by Clean, Fast, and Efficient Spectrophotometric Method. Journal of Analytical Methods in Chemistry No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1170300
American Medical Association (AMA)
de Aléssio, Patrícia Vidal& Kogawa, Ana Carolina& Salgado, Hérida Regina Nunes. Quality of Ceftriaxone Sodium in Lyophilized Powder for Injection Evaluated by Clean, Fast, and Efficient Spectrophotometric Method. Journal of Analytical Methods in Chemistry. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1170300
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170300