Selenium Supplementation, Body Mass Composition, and Leptin Levels in Patients with Obesity on a Balanced Mildly Hypocaloric Diet: A Pilot Study
Joint Authors
Vettor, Roberto
Pezzani, Raffaele
Censi, Simona
Manso, Jacopo
Mian, Caterina
Cavedon, Elisabetta
Negro, Isabella
Serra, Roberto
Busetto, Luca
Nacamulli, Davide
Plebani, Mario
Source
International Journal of Endocrinology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Adequate levels of selenium (Se) have protective effects against several chronic diseases, such as obesity.
The aim of this study was to assess the effect of Se supplementation in a selected group of patients with obesity.
Methods.
This randomized prospective study included 37 overweight/obese individuals aged 18–65 years, who adopted a slightly hypocaloric diet for 3 months.
An intervention group received 240 μg/day of L-selenomethionine for 3 months; a control group received a placebo.
Clinical and biochemical parameters, body composition measurements, and the Psychological General Well-Being Index (PGWBI) questionnaire were tested at the beginning and end of the treatment.
Results.
A comparison of the two groups showed a significant change in body composition, involving a decrease in body fat mass, between the baseline and the end of the follow-up, in the intervention group.
Unlike the placebo group, the group given Se had a significant increase in lean body and muscle mass and a significant decrease in leptin levels after 3 months on diet.
At the end of the follow-up, the group given Se scored higher on the PGWBI than those who did not.
Conclusion.
Se could reinforce the effects of diet for overweight and obesity.
This work was registered in the ISRCTN registry with study ID ISRCTN6106073.
American Psychological Association (APA)
Cavedon, Elisabetta& Manso, Jacopo& Negro, Isabella& Censi, Simona& Serra, Roberto& Busetto, Luca…[et al.]. 2020. Selenium Supplementation, Body Mass Composition, and Leptin Levels in Patients with Obesity on a Balanced Mildly Hypocaloric Diet: A Pilot Study. International Journal of Endocrinology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1170320
Modern Language Association (MLA)
Cavedon, Elisabetta…[et al.]. Selenium Supplementation, Body Mass Composition, and Leptin Levels in Patients with Obesity on a Balanced Mildly Hypocaloric Diet: A Pilot Study. International Journal of Endocrinology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1170320
American Medical Association (AMA)
Cavedon, Elisabetta& Manso, Jacopo& Negro, Isabella& Censi, Simona& Serra, Roberto& Busetto, Luca…[et al.]. Selenium Supplementation, Body Mass Composition, and Leptin Levels in Patients with Obesity on a Balanced Mildly Hypocaloric Diet: A Pilot Study. International Journal of Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1170320
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170320