Quantitative Aspect of Leucophyllum frutescens Fraction before and after Encapsulation in Polymeric Nanoparticles
Joint Authors
Rivas Morales, Catalina
Elaissari, Abdelhamid
Galindo-Rodríguez, Sergio Arturo
Álvarez-Román, Rocío
Martínez-Rivas, Claudia Janeth
Fessi, Hatem
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The interest on plants has been focalized due to their biological activities.
Extracts or fractions from plants in biodegradable polymeric nanoparticles (NP) provide many advantages on application studies.
The encapsulation of the extract or fraction in NP is determined for the establishment of the test dose.
HPLC method is an alternative to calculate this parameter.
An analytical method based on HPLC for quantification of a hexane fraction from L.
frutescens was developed and validated according to ICH.
Different concentrations of the hexane fraction from leaves (HFL) were prepared (100–600 μg/mL).
Linearity, limit of detection, limit of quantification, and intra- and interday precision parameters were determined.
HFL was encapsulated by nanoprecipitation technique and analyzed by HPLC for quantitative aspect.
The method was linear and precise for the quantification of the HFL components.
NP size was 190 nm with homogeneous size distribution.
Through validation method, it was determined that the encapsulation of components (1), (2), (3), and (4) was 44, 74, 86, and 97%, respectively.
A simple, repeatable, and reproducible methodology was developed for the propose of quantifying the components of a vegetable material loaded in NP, using as a model the hexane fraction of L.
frutescens leaves.
American Psychological Association (APA)
Martínez-Rivas, Claudia Janeth& Álvarez-Román, Rocío& Rivas Morales, Catalina& Elaissari, Abdelhamid& Fessi, Hatem& Galindo-Rodríguez, Sergio Arturo. 2017. Quantitative Aspect of Leucophyllum frutescens Fraction before and after Encapsulation in Polymeric Nanoparticles. Journal of Analytical Methods in Chemistry،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1170341
Modern Language Association (MLA)
Martínez-Rivas, Claudia Janeth…[et al.]. Quantitative Aspect of Leucophyllum frutescens Fraction before and after Encapsulation in Polymeric Nanoparticles. Journal of Analytical Methods in Chemistry No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1170341
American Medical Association (AMA)
Martínez-Rivas, Claudia Janeth& Álvarez-Román, Rocío& Rivas Morales, Catalina& Elaissari, Abdelhamid& Fessi, Hatem& Galindo-Rodríguez, Sergio Arturo. Quantitative Aspect of Leucophyllum frutescens Fraction before and after Encapsulation in Polymeric Nanoparticles. Journal of Analytical Methods in Chemistry. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1170341
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170341