Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis
Joint Authors
Aguilar-Luis, Miguel Angel
del Valle-Mendoza, Juana
Arévalo-Híjar, Lucía
Caballero-García, Stefany
Gonzáles-Soto, Néstor
Source
International Journal of Dentistry
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-25
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To evaluate antibacterial and cytotoxic effect of 2 methanolic extracts of Azadirachta indica and Moringa oleifera against strains of Enterococcus faecalis (ATCC 29212) in vitro.
Methods.
The methanolic extracts of Azadirachta indica and Moringa oleifera were prepared in vitro.
The antibacterial effect of the extracts against Enterococcus faecalis was evaluated using the agar diffusion technique.
The minimum inhibitory concentration (MIC) was determined using the microdilution method and the cytotoxicity using the cellular line MDCK.
Results.
The methanolic extract with the most antibacterial effect during the first 24 and 48 hours against Enterococcus faecalis was Moringa oleifera, evidencing a growth inhibition zone of 35.5 ± 1.05 and 44.83 ± 0.98, respectively.
The MIC for both extracts was 75 µg/ml.
The bactericidal effect of the Azadirachta indica extract was found at a concentration of 25 µg/ml and a concentration of 75 µg/ml for Moringa extract.
Conclusions.
In conclusion, we demonstrated that the methanolic extract of Azadirachta indica and Moringa oleifera both have an antibacterial effect against Enterococcus faecalis strains during the first 24 and 48 hours.
None of the extracts exhibited toxicity against the cell lines under low concentrations.
American Psychological Association (APA)
Arévalo-Híjar, Lucía& Aguilar-Luis, Miguel Angel& Caballero-García, Stefany& Gonzáles-Soto, Néstor& del Valle-Mendoza, Juana. 2018. Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis. International Journal of Dentistry،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1170379
Modern Language Association (MLA)
Arévalo-Híjar, Lucía…[et al.]. Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis. International Journal of Dentistry No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1170379
American Medical Association (AMA)
Arévalo-Híjar, Lucía& Aguilar-Luis, Miguel Angel& Caballero-García, Stefany& Gonzáles-Soto, Néstor& del Valle-Mendoza, Juana. Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis. International Journal of Dentistry. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1170379
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170379