Variation of Energy in Photobiomodulation for the Control of Radiotherapy-Induced Oral Mucositis: A Clinical Study in Head and Neck Cancer Patients
Joint Authors
Sabino-Silva, Robinson
de Freitas Filho, Silas Antonio Juvencio
Guedes, Cizelene do Carmo Faleiros Veloso
de Faria, Paulo Rogério
Loyola, Adriano Mota
Cardoso, Sérgio Vitorino
Source
International Journal of Dentistry
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Oral mucositis (OM) is a frequent and severe adverse effect of therapy against head and neck cancer.
Photobiomodulation with the low-power laser is known to be effective against OM, but the diversity of protocols and the possibility of stimulating residual tumor cells are still obstacles.
The present study aimed to compare two doses of laser energy delivered to the oral mucosa of patients under oncologic treatment for head and neck cancer, looking for differences in the control of mucositis, as well as in the frequency of tumoral recurrences.
Fifty-eight patients undergoing radiotherapy were randomized into two groups, distinguished according to the energy delivered by laser irradiation, namely, 0.25 J and 1.0 J.
The groups were compared according to frequency, severity, or duration of OM, as well as the frequency of tumoral recurrences.
OM was significantly less frequent in patients receiving 1.0 J of energy, but the groups did not differ regarding severity or duration of OM.
Tumoral recurrence also did not vary significantly between the groups.
Photobiomodulation with a higher dose of energy (1.0 J versus 0.25 J) is associated with better control of radiotherapy-induced OM and does not significantly increase the risk of neoplastic recurrence.
American Psychological Association (APA)
Guedes, Cizelene do Carmo Faleiros Veloso& de Freitas Filho, Silas Antonio Juvencio& de Faria, Paulo Rogério& Loyola, Adriano Mota& Sabino-Silva, Robinson& Cardoso, Sérgio Vitorino. 2018. Variation of Energy in Photobiomodulation for the Control of Radiotherapy-Induced Oral Mucositis: A Clinical Study in Head and Neck Cancer Patients. International Journal of Dentistry،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1170509
Modern Language Association (MLA)
Guedes, Cizelene do Carmo Faleiros Veloso…[et al.]. Variation of Energy in Photobiomodulation for the Control of Radiotherapy-Induced Oral Mucositis: A Clinical Study in Head and Neck Cancer Patients. International Journal of Dentistry No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1170509
American Medical Association (AMA)
Guedes, Cizelene do Carmo Faleiros Veloso& de Freitas Filho, Silas Antonio Juvencio& de Faria, Paulo Rogério& Loyola, Adriano Mota& Sabino-Silva, Robinson& Cardoso, Sérgio Vitorino. Variation of Energy in Photobiomodulation for the Control of Radiotherapy-Induced Oral Mucositis: A Clinical Study in Head and Neck Cancer Patients. International Journal of Dentistry. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1170509
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170509