Dentine Tubule Occlusion by Novel Bioactive Glass-Based Toothpastes
Joint Authors
Gillam, D. G.
Hill, Robert G.
da Cruz, Luiza Pereira Dias
Chen, Xiaojing
Source
International Journal of Dentistry
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-04
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
There are numerous over-the-counter (OTC) and professionally applied (in-office) products and techniques currently available for the treatment of dentine hypersensitivity (DH), but more recently, the use of bioactive glasses in toothpaste formulations have been advocated as a possible solution to managing DH.
Aim.
The aim of the present study, therefore, was to compare several bioactive glass formulations to investigate their effectiveness in an established in vitro model.
Materials and Methods.
A 45S5 glass was synthesized in the laboratory together with several other glass formulations: (1) a mixed glass (fluoride and chloride), (2) BioMinF, (3) a chloride glass, and (4) an amorphous chloride glass.
The glass powders were formulated into five different toothpaste formulations.
Dentine discs were sectioned from extracted human teeth and prepared for the investigation by removing the cutting debris (smear layer) following sectioning using a 6% citric acid solution for 2 minutes.
Each disc was halved to provide test and control halves for comparison following the brushing of the five toothpaste formulations onto the test halves for each toothpaste group.
Following the toothpaste application, the test discs were immersed in either artificial saliva or exposed to an acid challenge.
Results.
The dentine samples were analyzed using scanning electron microscopy (SEM), and observation of the SEM images indicated that there was good surface coverage following artificial saliva immersion.
Furthermore, although the acid challenge removed the hydroxyapatite layer on the dentine surface for most of the samples, except for the amorphous chloride glass, there was evidence of tubular occlusion in the dentine tubules.
Conclusions.
The conclusions from the study would suggest that the inclusion of bioactive glass into a toothpaste formulation may be an effective approach to treat DH.
American Psychological Association (APA)
da Cruz, Luiza Pereira Dias& Hill, Robert G.& Chen, Xiaojing& Gillam, D. G.. 2018. Dentine Tubule Occlusion by Novel Bioactive Glass-Based Toothpastes. International Journal of Dentistry،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1170557
Modern Language Association (MLA)
da Cruz, Luiza Pereira Dias…[et al.]. Dentine Tubule Occlusion by Novel Bioactive Glass-Based Toothpastes. International Journal of Dentistry No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1170557
American Medical Association (AMA)
da Cruz, Luiza Pereira Dias& Hill, Robert G.& Chen, Xiaojing& Gillam, D. G.. Dentine Tubule Occlusion by Novel Bioactive Glass-Based Toothpastes. International Journal of Dentistry. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1170557
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170557