Vitamin D Deficiency as It Relates to Oral Immunity and Chronic Periodontitis
Joint Authors
Feller, Liviu
Jadwat, Yusuf
Fourie, J.
Lemmer, J.
Ballyram, R.
Khammissa, Razia A. G.
Source
International Journal of Dentistry
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The biologically active form of vitamin D, 1,25 dihydroxyvitamin D (1,25(OH)2D) and its receptor, the vitamin D receptor (VDR), play roles in maintaining oral immunity and the integrity of the periodontium.
Results of observational cross-sectional clinical studies investigating the association between vitamin D serum level and the incidence and severity of chronic periodontitis indicate that, perhaps owing to the immunomodulatory, anti-inflammatory, and antibacterial properties of 1,25(OH)2 D/VDR signalling, a sufficient serum level of vitamin D is necessary for the maintenance of periodontal health.
In cases of established chronic periodontitis, vitamin D supplementation is associated with reduction in the severity of periodontitis.
As cross-sectional studies provide only weak evidence for any causal association and therefore are of questionable value, either longitudinal cohort studies, case controlled studies, or randomized control trials are needed to determine whether or not deficiency of vitamin D is a risk factor for chronic periodontitis, and whether or not vitamin D supplementation adjunctive to standard periodontal treatment is in any way beneficial.
In this article, we discuss the relationship between vitamin D, oral immunity and periodontal disease and review the rationale for using vitamin D supplementation to help maintain periodontal health and as an adjunct to standard periodontal treatment.
American Psychological Association (APA)
Khammissa, Razia A. G.& Ballyram, R.& Jadwat, Yusuf& Fourie, J.& Lemmer, J.& Feller, Liviu. 2018. Vitamin D Deficiency as It Relates to Oral Immunity and Chronic Periodontitis. International Journal of Dentistry،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1170637
Modern Language Association (MLA)
Khammissa, Razia A. G.…[et al.]. Vitamin D Deficiency as It Relates to Oral Immunity and Chronic Periodontitis. International Journal of Dentistry No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1170637
American Medical Association (AMA)
Khammissa, Razia A. G.& Ballyram, R.& Jadwat, Yusuf& Fourie, J.& Lemmer, J.& Feller, Liviu. Vitamin D Deficiency as It Relates to Oral Immunity and Chronic Periodontitis. International Journal of Dentistry. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1170637
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170637