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Exceptional Enlargement of the Mitochondrial Genome Results from Distinct Causes in Different Rain Frogs (Anura: Brevicipitidae: Breviceps)
Joint Authors
Kurabayashi, Atsushi
Hemmi, Keitaro
Kakehashi, Ryosuke
Kambayashi, Chiaki
Du Preez, Louis
Minter, Leslie
Furuno, Nobuaki
Source
International Journal of Genomics
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-23
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The mitochondrial (mt) genome of the bushveld rain frog (Breviceps adspersus, Brevicipitidae, Afrobatrachia) is the largest (28.8 kbp) among the vertebrates investigated to date.
The major cause of genome size enlargement in this species is the duplication of multiple genomic regions.
To investigate the evolutionary lineage, timing, and process of mt genome enlargement, we sequenced the complete mtDNAs of two congeneric rain frogs, B.
mossambicus and B.
poweri.
The mt genomic organization, gene content, and gene arrangements of these two rain frogs are very similar to each other but differ from those of B.
adspersus.
The B.
mossambicus mt genome (22.5 kbp) does not differ significantly from that of most other afrobatrachians.
In contrast, the B.
poweri mtDNA (28.1 kbp) is considerably larger: currently the second largest among vertebrates, after B.
adspersus.
The main causes of genome enlargement differ among Breviceps species.
Unusual elongation (12.5 kbp) of the control region (CR), a single major noncoding region of the vertebrate mt genome, is responsible for the extremely large mt genome in B.
poweri.
Based on the current Breviceps phylogeny and estimated divergence age, it can be concluded that the genome enlargements occurred independently in each species lineage within relatively short periods.
Furthermore, a high nucleotide substitution rate and relaxation of selective pressures, which are considered to be involved in changes in genome size, were also detected in afrobatrachian lineages.
Our results suggest that these factors were not direct causes but may have indirectly affected mt genome enlargements in Breviceps.
American Psychological Association (APA)
Hemmi, Keitaro& Kakehashi, Ryosuke& Kambayashi, Chiaki& Du Preez, Louis& Minter, Leslie& Furuno, Nobuaki…[et al.]. 2020. Exceptional Enlargement of the Mitochondrial Genome Results from Distinct Causes in Different Rain Frogs (Anura: Brevicipitidae: Breviceps). International Journal of Genomics،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1171286
Modern Language Association (MLA)
Hemmi, Keitaro…[et al.]. Exceptional Enlargement of the Mitochondrial Genome Results from Distinct Causes in Different Rain Frogs (Anura: Brevicipitidae: Breviceps). International Journal of Genomics No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1171286
American Medical Association (AMA)
Hemmi, Keitaro& Kakehashi, Ryosuke& Kambayashi, Chiaki& Du Preez, Louis& Minter, Leslie& Furuno, Nobuaki…[et al.]. Exceptional Enlargement of the Mitochondrial Genome Results from Distinct Causes in Different Rain Frogs (Anura: Brevicipitidae: Breviceps). International Journal of Genomics. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1171286
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171286