In Vitro Antileishmanial Activity and GC-MS Analysis of Whole Plant Hexane Fraction of Achillea wilhelmsii (WHFAW)
Joint Authors
Anwar, Mohammad
Achakzai, Jahangir Khan
Kakar, Abdul Manan
Kakar, Shahabuddin
Khan, Javed
Khan, Nazima Yousaf
Akhtar, Basira
Khan, Ghulam Mustafa
Baloch, Nizam
Jan Khoso, Muhammad Hashim
Panezai, Marina
Akbar, Ali
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-26, 26 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-01
Country of Publication
Egypt
No. of Pages
26
Main Subjects
Abstract EN
In this study, GC-MS analysis has shown that whole plant hexane fraction of Achillea wilhelmsii (WHFAW) consists of 66 compounds which exhibited antileishmanial activity.
Antileishmanial bioassay was the method used for determining antileishmanial activity.
The inhibitory concentration (IC50) which was observed for whole plant hexane fraction of Achillea wilhelmsii (WHFAW) against parasitic and vector-borne disease, leishmaniasis, is 58.27 ± 0.52 μg/mL.
For leishmanicidal assay, Leishmania major is the species used for analysis.
Whole plant methanol extract of Achillea wilhelmsii (WMEAW) and whole plant aqueous fraction of Achillea wilhelmsii (WAFAW) exhibited no antileishmanial activity.
American Psychological Association (APA)
Achakzai, Jahangir Khan& Anwar, Mohammad& Kakar, Abdul Manan& Akhtar, Basira& Akbar, Ali& Kakar, Shahabuddin…[et al.]. 2019. In Vitro Antileishmanial Activity and GC-MS Analysis of Whole Plant Hexane Fraction of Achillea wilhelmsii (WHFAW). Journal of Chemistry،Vol. 2019, no. 2019, pp.1-26.
https://search.emarefa.net/detail/BIM-1171291
Modern Language Association (MLA)
Achakzai, Jahangir Khan…[et al.]. In Vitro Antileishmanial Activity and GC-MS Analysis of Whole Plant Hexane Fraction of Achillea wilhelmsii (WHFAW). Journal of Chemistry No. 2019 (2019), pp.1-26.
https://search.emarefa.net/detail/BIM-1171291
American Medical Association (AMA)
Achakzai, Jahangir Khan& Anwar, Mohammad& Kakar, Abdul Manan& Akhtar, Basira& Akbar, Ali& Kakar, Shahabuddin…[et al.]. In Vitro Antileishmanial Activity and GC-MS Analysis of Whole Plant Hexane Fraction of Achillea wilhelmsii (WHFAW). Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-26.
https://search.emarefa.net/detail/BIM-1171291
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171291
