Adaptive Modifications of Maternal Hypothalamic-Pituitary-Adrenal Axis Activity during Lactation and Salsolinol as a New Player in this Phenomenon
Joint Authors
Hasiec, Malgorzata
Misztal, Tomasz
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Both basal and stress-induced secretory activities of the hypothalamic-pituitary-adrenal (HPA) axis are distinctly modified in lactating females.
On the one hand, it aims to meet the physiological demands of the mother, and on the other hand, the appropriate and stable plasma cortisol level is one of the essential factors for the proper offspring development.
Specific adaptations of HPA axis activity to lactation have been extensively studied in several animal species and humans, providing interesting data on the HPA axis plasticity mechanism.
However, most of the data related to this phenomenon are derived from studies in rats.
The purpose of this review is to highlight these adaptations, with a particular emphasis on stress reaction and differences that occur between species.
Existing data on breastfeeding women are also included in several aspects.
Finally, data from the experiments in sheep are presented, indicating a new regulatory factor of the HPA axis—salsolinol—which typical role was revealed in lactation.
It is suggested that this dopamine derivative is involved in both maintaining basal and suppressing stress-induced HPA axis activities in lactating dams.
American Psychological Association (APA)
Hasiec, Malgorzata& Misztal, Tomasz. 2018. Adaptive Modifications of Maternal Hypothalamic-Pituitary-Adrenal Axis Activity during Lactation and Salsolinol as a New Player in this Phenomenon. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1171293
Modern Language Association (MLA)
Hasiec, Malgorzata& Misztal, Tomasz. Adaptive Modifications of Maternal Hypothalamic-Pituitary-Adrenal Axis Activity during Lactation and Salsolinol as a New Player in this Phenomenon. International Journal of Endocrinology No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1171293
American Medical Association (AMA)
Hasiec, Malgorzata& Misztal, Tomasz. Adaptive Modifications of Maternal Hypothalamic-Pituitary-Adrenal Axis Activity during Lactation and Salsolinol as a New Player in this Phenomenon. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1171293
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171293