Comparative Metabolomics Study Revealed Difference in Central Carbon Metabolism between Sika Deer and Red Deer Antler
Joint Authors
Zhang, He
Zhao, Daqing
Su, Hang
Yang, Chonghui
Jin, Chenrong
Yin, Chengcheng
Yang, Yang
Chen, Haoyuan
Jing, Li
Qi, Bin
Bai, Xueyuan
Liu, Li
Source
International Journal of Genomics
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The antler regeneration has been well studied for the past two decades and adopted in the regenerative medicine model for studying on developmental biology.
Despite our growing knowledge of functional molecules regulating antler regeneration, we still do not know whether antler from different deer species possess the exact same mechanism or not.
Our previous comparative study between sika deer and red deer suggests that the metabolic pathways between them are profoundly different based on protein level.
Therefore, the metabolomic technology is used to identify and quantify the metabolites in antler samples, providing interesting insights into differential metabolite profile of antlers between sika deer and red deer.
The distinct metabolic characteristics of sika deer compared to red deer provide an opportunity to explain why the red deer antler with a larger size.
The enrichment analysis of differential metabolites showed that three pathways including glycine and serine metabolism, methionine metabolism, and pterine biosynthesis had a significant difference between two antler groups.
American Psychological Association (APA)
Su, Hang& Yang, Chonghui& Jin, Chenrong& Zhang, He& Yin, Chengcheng& Yang, Yang…[et al.]. 2020. Comparative Metabolomics Study Revealed Difference in Central Carbon Metabolism between Sika Deer and Red Deer Antler. International Journal of Genomics،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1171305
Modern Language Association (MLA)
Su, Hang…[et al.]. Comparative Metabolomics Study Revealed Difference in Central Carbon Metabolism between Sika Deer and Red Deer Antler. International Journal of Genomics No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1171305
American Medical Association (AMA)
Su, Hang& Yang, Chonghui& Jin, Chenrong& Zhang, He& Yin, Chengcheng& Yang, Yang…[et al.]. Comparative Metabolomics Study Revealed Difference in Central Carbon Metabolism between Sika Deer and Red Deer Antler. International Journal of Genomics. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1171305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171305