Pre- and Postoperative Body Composition and Metabolic Characteristics in Patients with Acromegaly: A Prospective Study
Joint Authors
Guo, Xiaopeng
Xing, Bing
Gao, Lu
Wang, Zihao
Shi, Xiaodong
Li, Hailong
Wang, Qiang
Chen, Wei
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
To investigate the preoperative body composition, metabolic characteristics, and postoperative changes in patients with active acromegaly and analyze the effects of gender and age.
Methods.
We included 36 patients with untreated acromegaly and 37 patients with nonfunctional pituitary adenomas.
Adipose tissue (AT), the visceral fat index (VFI), sclerotin, protein, skeletal muscle, total body water (TBW), intracellular water (ICW), and extracellular water (ECW) were measured using bioelectrical impedance analysis (BIA).
Total energy expenditure (TEE) and basal metabolism (BM) were measured with a cardiopulmonary and metabolic analyzer (CMA).
Tricep skinfold thickness (TST), bicep circumference, waistline, hipline, and calf circumference were measured with a skinfold caliper and tape.
These indices were measured before surgery and 3 months and 1 year after surgery.
Results.
Overall, AT, VFI, and TST were lower, whereas sclerotin, protein, skeletal muscle, TBW, ICW, ECW, TEE, and BM were higher in acromegaly patients.
Postoperatively, TST rose initially and then decreased, the waistline increased, and sclerotin, skeletal muscle, TEE, and BM decreased.
Changes in these indices differed with gender and age in unique patterns.
Conclusions.
Body composition and metabolism in acromegaly patients changed after surgery, and gender and age influenced these changes.
American Psychological Association (APA)
Guo, Xiaopeng& Gao, Lu& Shi, Xiaodong& Li, Hailong& Wang, Qiang& Wang, Zihao…[et al.]. 2018. Pre- and Postoperative Body Composition and Metabolic Characteristics in Patients with Acromegaly: A Prospective Study. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1171312
Modern Language Association (MLA)
Guo, Xiaopeng…[et al.]. Pre- and Postoperative Body Composition and Metabolic Characteristics in Patients with Acromegaly: A Prospective Study. International Journal of Endocrinology No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1171312
American Medical Association (AMA)
Guo, Xiaopeng& Gao, Lu& Shi, Xiaodong& Li, Hailong& Wang, Qiang& Wang, Zihao…[et al.]. Pre- and Postoperative Body Composition and Metabolic Characteristics in Patients with Acromegaly: A Prospective Study. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1171312
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171312