The High Prevalence of Negative Hepatitis B Surface Antibody (Anti-HBs) among Pregnant Women in Bandung, Indonesia: A Community-Based Study
Joint Authors
Prasetyo, Dwi
Judistiani, Raden Tina Dewi
Girawan, Dolvy
Risan, Nelly A.
Bestari, Muhammad B.
Nugraha, Eka S.
Ermaya, Yudith S.
Source
International Journal of Hepatology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Hepatitis B virus (HBV) infection is a disease that creates a high global burden by affecting approximately 3.5% of the total world population.
The main transmission of this disease is from mother to child (MTCT).
HBV vaccination program was already initiated in Indonesia in 1987.
However, after three decades, the HBV infection prevalence stays stagnant.
This study aimed to explore the seroprevalence of HBV markers and the attributable risk factors of pregnant women at risk of transmitting HBV to their offspring.
Method.
A cross-sectional study was conducted on pregnant women from primary midwifery and obstetric clinics across Bandung, Indonesia, to assess the HBsAg, anti-HBc, and anti-HBs serological markers.
Questionnaire-based interviews were used to obtain the sociodemographic determinants.
Logistic regression was applied to assess the association of each determinant factor to positive HBsAg or negative anti-HBs as a dependent variable, which was then reported as odds ratios (OR).
Results.
A total of 196 subjects were recruited with 12/196 (6.1%) of them were positive HBsAg.
After exclusions of those with positive HBsAg and anti-HBc, 24/175 (13.7%) women were isolated as positive anti-HBs, leaving 151/175 (86.3%) women with negative anti-HBs who were susceptible to HBV infection.
Low body mass index (BMI) less than 18.5 kg/m2 was a risk factor for positive HBsAg with OR=5.850 (95% CI 1.466-23.34), p=0.012.
Nevertheless, no significant determinant factor was associated with negative anti-HBs.
Conclusion.
Most pregnant women in Bandung, Indonesia, are susceptible to HBV infection, as marked by the negative anti-HBs status.
American Psychological Association (APA)
Girawan, Dolvy& Judistiani, Raden Tina Dewi& Risan, Nelly A.& Bestari, Muhammad B.& Nugraha, Eka S.& Ermaya, Yudith S.…[et al.]. 2020. The High Prevalence of Negative Hepatitis B Surface Antibody (Anti-HBs) among Pregnant Women in Bandung, Indonesia: A Community-Based Study. International Journal of Hepatology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1171438
Modern Language Association (MLA)
Girawan, Dolvy…[et al.]. The High Prevalence of Negative Hepatitis B Surface Antibody (Anti-HBs) among Pregnant Women in Bandung, Indonesia: A Community-Based Study. International Journal of Hepatology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1171438
American Medical Association (AMA)
Girawan, Dolvy& Judistiani, Raden Tina Dewi& Risan, Nelly A.& Bestari, Muhammad B.& Nugraha, Eka S.& Ermaya, Yudith S.…[et al.]. The High Prevalence of Negative Hepatitis B Surface Antibody (Anti-HBs) among Pregnant Women in Bandung, Indonesia: A Community-Based Study. International Journal of Hepatology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1171438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171438