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Porous Cellulose Beads Fabricated from Regenerated Cellulose as Potential Drug Delivery Carriers
Joint Authors
Pang, Suh Cem
Chin, Suk Fun
Voon, Lee Ken
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-26
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Highly porous cellulose beads (CBs) of various mean sizes were successfully prepared from regenerated cellulose of paper wastes.
The drug delivery characteristics of CBs with different mean sizes were investigated using curcumin as the model drug under controlled conditions.
The loading capacity and efficiency of curcumin onto CBs were substantially influenced by factors such as their morphological characteristics, curcumin concentration, and duration of loading.
The release kinetic profiles of curcumin from CBs of different mean sizes were investigated in media of pH values resembling digestive juices and intestinal fluids.
Release kinetic models were used to simulate and elucidate release kinetics and mechanisms of curcumin from CBs under specific conditions.
The loading capacity and efficiency of curcumin onto CBs could be enhanced via the optimization of curcumin solution concentration and the morphological characteristics of CBs, whereas the release kinetic profiles of curcumin from CBs could be modulated by varying the mean diameter of CBs.
Optimized CBs derived from regenerated cellulose of paper wastes are potentially useful as cost-effective drug delivery carriers.
American Psychological Association (APA)
Voon, Lee Ken& Pang, Suh Cem& Chin, Suk Fun. 2017. Porous Cellulose Beads Fabricated from Regenerated Cellulose as Potential Drug Delivery Carriers. Journal of Chemistry،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1171453
Modern Language Association (MLA)
Voon, Lee Ken…[et al.]. Porous Cellulose Beads Fabricated from Regenerated Cellulose as Potential Drug Delivery Carriers. Journal of Chemistry No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1171453
American Medical Association (AMA)
Voon, Lee Ken& Pang, Suh Cem& Chin, Suk Fun. Porous Cellulose Beads Fabricated from Regenerated Cellulose as Potential Drug Delivery Carriers. Journal of Chemistry. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1171453
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171453