Combination of Maximum Shear Wave Elasticity Modulus and TIRADS Improves the Diagnostic Specificity in Characterizing Thyroid Nodules: A Retrospective Study
Joint Authors
Du, Lian-Fang
Qiao, Xiao-Hui
Li, Fan
Hang, Jing
Ye, Xin-hua
Li, Ao
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
The present study is aimed at evaluating the diagnostic value of combining shear wave elastography (SWE) parameters and the thyroid imaging reporting and data system (TIRADS) for differentiating between benign and malignant thyroid nodules.
Methods.
Patients who underwent conventional ultrasonography (US) and SWE before surgery were enrolled in the current study.
Each nodule was given a TIRADS risk score.
The effectiveness of the SWE parameters was assessed by odds ratios (ORs).
The SWE scoring risk stratification was proposed beyond 95% probability, and the desired values were obtained according to the log-normal distribution.
The area under the receiver-operating characteristic (AUC) was used to compare the diagnostic performance between TIRADS-alone and TIRADS + SWE.
Results.
A total of 262 patients with 298 thyroid nodules were enrolled in our study.
The pathological analyses were conducted on 121 benign and 177 malignant nodules.
The AUC values for TIRADS-alone and TIRADS + SWE were 0.896 (accuracy 83.2%) and 0.917 (accuracy 84.2%), respectively.
However, the TIRADS + SWE scores showed a higher specificity (88.4%) and positive predictive value (91.2%) as compared with the TIRADS-alone of 73.6% and 83.2%, respectively.
Conclusions.
Combining SWE and TIRADS improves the specificity of TIRADS-alone in differentiating between benign and malignant thyroid nodules.
American Psychological Association (APA)
Hang, Jing& Li, Fan& Qiao, Xiao-Hui& Ye, Xin-hua& Li, Ao& Du, Lian-Fang. 2018. Combination of Maximum Shear Wave Elasticity Modulus and TIRADS Improves the Diagnostic Specificity in Characterizing Thyroid Nodules: A Retrospective Study. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1171478
Modern Language Association (MLA)
Hang, Jing…[et al.]. Combination of Maximum Shear Wave Elasticity Modulus and TIRADS Improves the Diagnostic Specificity in Characterizing Thyroid Nodules: A Retrospective Study. International Journal of Endocrinology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1171478
American Medical Association (AMA)
Hang, Jing& Li, Fan& Qiao, Xiao-Hui& Ye, Xin-hua& Li, Ao& Du, Lian-Fang. Combination of Maximum Shear Wave Elasticity Modulus and TIRADS Improves the Diagnostic Specificity in Characterizing Thyroid Nodules: A Retrospective Study. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1171478
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171478