Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study
Joint Authors
Xie, Huijian
Wang, Xinya
He, Yan
Huang, Daoyi
Qu, Xinyuan
Jiang, Yanbo
An, Yan
Zhang, Shaoyan
Zhang, Mingzhi
Source
International Journal of Hypertension
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Up to date, human urotensin II (UII) is the most potent vasoconstrictor in mammalian animals.
To explore whether UII played an important role in the development of hypertension, we conducted a prospective study in Changshu city, China.
The baseline investigation was carried out in 2007, and the first follow-up investigation was conducted in 2013.
From the participants, we randomly obtained 2000 normotensive subjects aged 40 years and older without any severe disease at baseline and examined plasma UII and endothelin-1 (ET-1) with their blood samples at baseline.
Logistic models were used to analyze the association between baseline UII, baseline ET-1, and newly occurring hypertension.
In 1,819 subjects with complete data, 723 subjects developed into hypertensive in about five years.
After adjusting some potential confounders, the odds ratio (95% confidence interval) for risk of hypertension comparing the highest with the lowest quartile of baseline UII was 0.888 (0.689–1.144).
The role of UII in the development of hypertension was not found in the current study; therefore, further research studies should be conducted to explore the relationship between UII and hypertension.
American Psychological Association (APA)
Xie, Huijian& Wang, Xinya& He, Yan& Huang, Daoyi& Qu, Xinyuan& Jiang, Yanbo…[et al.]. 2020. Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study. International Journal of Hypertension،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1171624
Modern Language Association (MLA)
Xie, Huijian…[et al.]. Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study. International Journal of Hypertension No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1171624
American Medical Association (AMA)
Xie, Huijian& Wang, Xinya& He, Yan& Huang, Daoyi& Qu, Xinyuan& Jiang, Yanbo…[et al.]. Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study. International Journal of Hypertension. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1171624
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171624