The Association between Serum Bilirubin Level and Electrochemical Skin Conductance in Chinese Patients with Type 2 Diabetes
Joint Authors
Zhu, Xiaoming
Lu, Bin
Li, Yiming
Mao, Fei
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Bilirubin is an antioxidant and plays a protective role against cardiovascular and microvascular disease.
The aim of this study is to explore the possible protective effect of bilirubin on small nerve function.
A total of 265 Chinese patients with type 2 diabetes mellitus (T2DM) were enrolled in the study.
Both SUDOSCAN and other traditional diabetic neuropathy examinations including neuropathy symptom score (NSS), the neuropathy disability score (NDS) and Michigan Neuropathy Screening Instrument (MNSI) scores were performed in all patients with T2DM.
Blood bilirubin levels were tested in the study.
Spearman correlation analysis and multivariate regression analysis were performed to determine the relation between bilirubin level and hands and feet ESC values.
Spearman correlation analysis demonstrated a correlation between total bilirubin and ESC levels including hands (r=0.165, P<0.05) and feet (r=0.122, P<0.05) as well as between UCBil and ESC levels including both hands (r=0.172, P<0.05) and feet (r=0.175, P<0.05).
Multivariate regression linear analyses showed both total bilirubin and UCBil level were independently associated with hands and feet ESC levels.
All these results suggested a positive association between bilirubin level and ESC level, indicating a possible protective role of bilirubin in peripheral small nerve dysfunction of type 2 diabetes mellitus.
American Psychological Association (APA)
Mao, Fei& Zhu, Xiaoming& Lu, Bin& Li, Yiming. 2018. The Association between Serum Bilirubin Level and Electrochemical Skin Conductance in Chinese Patients with Type 2 Diabetes. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171747
Modern Language Association (MLA)
Mao, Fei…[et al.]. The Association between Serum Bilirubin Level and Electrochemical Skin Conductance in Chinese Patients with Type 2 Diabetes. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171747
American Medical Association (AMA)
Mao, Fei& Zhu, Xiaoming& Lu, Bin& Li, Yiming. The Association between Serum Bilirubin Level and Electrochemical Skin Conductance in Chinese Patients with Type 2 Diabetes. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171747
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171747