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Multivariant Crystallization of Tetraplatin Precursors from Solutions Containing 1,2-C6H10(NH3)2 2+ and [PtCl6]2– Ions
Joint Authors
Mulagaleev, R. F.
Leshok, D. Y.
Starkov, A. K.
Matsulev, A. N.
Kirik, S. D.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Seven new phases containing hexachloroplatinate [PtCl6]2− and trans-1,2-dl-diammoniumcyclohexane 1,2-C6H10NH322+ ions were obtained by crystallization from solutions with minor variation of synthesis conditions.
The compounds can be applied as precursors for the synthesis of effective anticancer drug tetraplatin ([PtC6H10(NH2)2Cl4]).
The phase diversity was achieved by alterations including solvent acidity, crystallization rate, temperature, type of solvent, and the reagents ratio.
The compounds were characterized by chemical and thermal analysis, IR, and 1H NMR spectroscopy.
Crystal structures of the five compounds were determined by X-ray powder diffraction technique.
The phases have ionic structures involving H2O, HCl molecules, or Cl− ions as supplementary species in the lattices.
It helps to arrange some frames additionally interconnected by hydrogen bonds between ions and solvent molecules.
It was suggested that crystal lattices adapted associated particles presented in solutions.
It results in observed variety of the crystal structures.
Besides the basic interest the obtained results are important for tetraplatin synthesis control.
American Psychological Association (APA)
Mulagaleev, R. F.& Leshok, D. Y.& Starkov, A. K.& Matsulev, A. N.& Kirik, S. D.. 2017. Multivariant Crystallization of Tetraplatin Precursors from Solutions Containing 1,2-C6H10(NH3)2 2+ and [PtCl6]2– Ions. Journal of Chemistry،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1171754
Modern Language Association (MLA)
Mulagaleev, R. F.…[et al.]. Multivariant Crystallization of Tetraplatin Precursors from Solutions Containing 1,2-C6H10(NH3)2 2+ and [PtCl6]2– Ions. Journal of Chemistry No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1171754
American Medical Association (AMA)
Mulagaleev, R. F.& Leshok, D. Y.& Starkov, A. K.& Matsulev, A. N.& Kirik, S. D.. Multivariant Crystallization of Tetraplatin Precursors from Solutions Containing 1,2-C6H10(NH3)2 2+ and [PtCl6]2– Ions. Journal of Chemistry. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1171754
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171754