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Chemical Constituents from the Roots of Polygala arillata and Their Anti-Inflammatory Activities
Joint Authors
Zhu, Yan
Wang, Chun-Hua
Xiang, Wei
Zhang, Guo-Dong
Li, Fang-Yi
Wang, Teng-long
Suo, Tong-Chuan
Li, Zheng
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A new compound, named arillatanoside E, which was elucidated as 3-O-β-D-glucopyranosyl presenegenin 28-O-β-D-xylopyranosyl-(1 ⟶ 3)-β-D-xylopyranosyl-(1 ⟶ 4)-α-L-rhamnopyranosyl-(1 ⟶ 2)-(4-O-acetyl)-β-D-fucopyranosyl ester, along with 11 known compounds was isolated from the ethanolic extract of the roots of Polygala arillata.
The 11 known compounds were identified as oleanolic acid (2), 3′-E-3,4,5-trimethoxy cinnamoyl-6-benzoyl sucrose (3), trans-ferulic acid (4), trans-feruloyl-glucoside (5), feruloyl-glucoside (6), 2,4,6-trimethoxy-1-O-β-D-glycoside (7), 3-methoxy-4-hydroxybenzoic acid (8), monopentadecanoin (9), sinapic acid (10), p-hydroxybenzaldehyde (11), and palmitic acid (12).
Among them, seven isolated compounds 1, 2, 4, 5, 7, 8, and 10 exhibited little cytotoxic activity on macrophage RAW 264.7 cells.
Then, the inhibitory effects of 7 isolates on nitric oxide (NO) production in lipopolysaccharide-activated macrophages were evaluated.
As a result, 3 compounds have significant anti-inflammatory activity, and they were arillatanoside E (1), oleanolic acid (2), and 2,4,6-trimethoxy-1-O-β-D-glycoside (7).
American Psychological Association (APA)
Xiang, Wei& Zhang, Guo-Dong& Li, Fang-Yi& Wang, Teng-long& Suo, Tong-Chuan& Wang, Chun-Hua…[et al.]. 2019. Chemical Constituents from the Roots of Polygala arillata and Their Anti-Inflammatory Activities. Journal of Chemistry،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1171764
Modern Language Association (MLA)
Xiang, Wei…[et al.]. Chemical Constituents from the Roots of Polygala arillata and Their Anti-Inflammatory Activities. Journal of Chemistry No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1171764
American Medical Association (AMA)
Xiang, Wei& Zhang, Guo-Dong& Li, Fang-Yi& Wang, Teng-long& Suo, Tong-Chuan& Wang, Chun-Hua…[et al.]. Chemical Constituents from the Roots of Polygala arillata and Their Anti-Inflammatory Activities. Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1171764
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171764