Efficacy, Safety, and Quality of Treatment Satisfaction of Premixed Human and Analogue Insulin Regimens in a Large Cohort of Type 2 Diabetic Patients: PROGENS BENEFIT Observational Study
Joint Authors
Tomasik, Andrzej
Masierek, Małgorzata
Sawczyn, Tomasz
Nabrdalik, Katarzyna
Kwiendacz, Hanna
Kukla, Michał
Gumprecht, Janusz
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Diabetes is a lifelong course disease, so insulin treatment has to be effective and safe, and patients should be satisfied with it.
We aimed to compare efficacy, safety, and quality of treatment satisfaction of human and premixed analogue insulin among 3264 patients (53.58% women) with type 2 diabetes mellitus (T2DM) in a real-life environment.
2493 patients (62.77%) had been assigned to group I where before the inclusion into the study the treatment regimen has been changed from analogue to human premixed insulin and 771 patients (37.23%) to group II where the treatment with insulin analogue remained unchanged.
At the end of the study, there was a reduction of HbA1c observed in both of the groups; however, Δ HbA1c was significantly higher in group 1 (−0.599 versus −0.406; P<0.001 at visit 3 versus visit 1).
The number of hypoglycemic episodes during the study observation was insignificantly reduced in both groups.
Diabetes treatment satisfaction measured with DTSQ increased at the end of the study and was significantly better in group I compared to group II (P<0.001).
This observational study proved that both human and premixed analogue insulin are effective and safe, and patients are satisfied with the treatment.
American Psychological Association (APA)
Nabrdalik, Katarzyna& Kwiendacz, Hanna& Sawczyn, Tomasz& Tomasik, Andrzej& Kukla, Michał& Masierek, Małgorzata…[et al.]. 2018. Efficacy, Safety, and Quality of Treatment Satisfaction of Premixed Human and Analogue Insulin Regimens in a Large Cohort of Type 2 Diabetic Patients: PROGENS BENEFIT Observational Study. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171807
Modern Language Association (MLA)
Nabrdalik, Katarzyna…[et al.]. Efficacy, Safety, and Quality of Treatment Satisfaction of Premixed Human and Analogue Insulin Regimens in a Large Cohort of Type 2 Diabetic Patients: PROGENS BENEFIT Observational Study. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171807
American Medical Association (AMA)
Nabrdalik, Katarzyna& Kwiendacz, Hanna& Sawczyn, Tomasz& Tomasik, Andrzej& Kukla, Michał& Masierek, Małgorzata…[et al.]. Efficacy, Safety, and Quality of Treatment Satisfaction of Premixed Human and Analogue Insulin Regimens in a Large Cohort of Type 2 Diabetic Patients: PROGENS BENEFIT Observational Study. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171807
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171807