The Influence of Obesity on Puberty and Insulin Resistance in Mexican Children
Joint Authors
Garza-Veloz, Idalia
Martinez-Fierro, Margarita L.
Galván-Tejada, Carlos E.
Cardenas-Vargas, Edith
Nava, Jairo A.
Torres-Castañeda, Mayra C.
Cid-Baez, Miguel A.
Castañeda-Arteaga, Rosa E.
Ortiz-Castro, Yolanda
Trejo-Ortiz, Perla M.
Araujo-Espino, Roxana
Mollinedo-Montaño, Fabiana E.
Muñoz-Torres, Jose R.
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Obesity is considered the main risk factor associated with the development of insulin resistance (IR).
The aim of this study was to evaluate the influence of obesity on puberty onset and IR in Mexican children.
A total of 378 children (189 boys and 189 girls) aged 8–14 years participated in the study.
IR was estimated using the homeostasis model assessment for IR (HOMA-IR).
The mean fasting glucose (FG) and basal insulin levels were 82 mg/dl and 11.0 μIU/ml in boys and 77.3 mg/dl and 12.3 μIU/ml in girls (P<0.05).
Subjects with obesity at Tanner stages II–V showed increased FG levels (P<0.05).
In boys with obesity, there was a decrease in HOMA-IR in Tanner stage IV and differences in age between boys with normal weight and those with obesity in Tanner V, being older the boys with obesity.
Obesity in children and adolescents was associated with higher HOMA-IR values.
In boys with obesity, IR increased at the end of pubertal maturation, with a delay in puberty.
These findings should be considered on the establishment of IR cutoff values for pubertal population in Mexico and in the establishment of strategies to prevent the health problems related to obesity.
American Psychological Association (APA)
Cardenas-Vargas, Edith& Nava, Jairo A.& Garza-Veloz, Idalia& Torres-Castañeda, Mayra C.& Galván-Tejada, Carlos E.& Cid-Baez, Miguel A.…[et al.]. 2018. The Influence of Obesity on Puberty and Insulin Resistance in Mexican Children. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1171877
Modern Language Association (MLA)
Cardenas-Vargas, Edith…[et al.]. The Influence of Obesity on Puberty and Insulin Resistance in Mexican Children. International Journal of Endocrinology No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1171877
American Medical Association (AMA)
Cardenas-Vargas, Edith& Nava, Jairo A.& Garza-Veloz, Idalia& Torres-Castañeda, Mayra C.& Galván-Tejada, Carlos E.& Cid-Baez, Miguel A.…[et al.]. The Influence of Obesity on Puberty and Insulin Resistance in Mexican Children. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1171877
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171877