Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population
Joint Authors
Turmukhambetova, A.
Akhmaltdinova, L.
Sirota, V.
Zhumaliyeva, V.
Babenko, D.
Kadyrova, I.
Tauesheva, Z.
Taizhanova, D.
Ibraeva, A.
Maratkyzy, M.
Source
International Journal of Inflammation
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Colorectal cancer is a type of oncopathology widespread in Kazakhstan.
The genetic component, as well as the possible etiopathogenetic mechanisms, is widely studied.
One of the most promising areas is the study of diagnostic and prognostic possibilities of inflammatory biomarkers in patients with different degrees of tumor differentiation.
The following biomarkers were included in the study panel: stem cell factor (SCF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF2), interleukin 6 (IL6), interleukin 8 (IL8), macrophage migration inhibitory factor (MIF), soluble Fas (SFAS), soluble Fas ligand (sFASL), transforming growth factor β (TGF), tumor necrosis factor (TNF), TNF-related apoptosis-inducing ligand (TRAIL), and programmed death ligand 1 (PD-L1).
The data of our study show that most of the basic proinflammatory cytokines are involved in the systemic process and their levels do not depend on the level of tissue differentiation.
Serum PD-L1 has shown itself to be a promising marker for tumor growth, which depends on the degree of differentiation.
American Psychological Association (APA)
Akhmaltdinova, L.& Sirota, V.& Zhumaliyeva, V.& Babenko, D.& Kadyrova, I.& Tauesheva, Z.…[et al.]. 2020. Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population. International Journal of Inflammation،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1171893
Modern Language Association (MLA)
Akhmaltdinova, L.…[et al.]. Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population. International Journal of Inflammation No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1171893
American Medical Association (AMA)
Akhmaltdinova, L.& Sirota, V.& Zhumaliyeva, V.& Babenko, D.& Kadyrova, I.& Tauesheva, Z.…[et al.]. Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population. International Journal of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1171893
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171893