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In Situ Preservation Fraction of Parathyroid Gland in Thyroidectomy: A Cohort Retrospective Study
Joint Authors
Luo, Han
Zhao, Wanjun
Yang, Hongliu
Su, Anping
Wang, Bin
Zhu, Jingqiang
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Objectives.
Parathyroid failure is the most common symptom after thyroidectomy.
To prevent it, a gland was preserved in situ or an ischemic one was autotransplanted.
This study explored the relationship between in situ preservation of the parathyroid gland and gland failure.
Methods.
Consecutive patients who underwent initial total thyroidectomy were enrolled retrospectively in a prospectively maintained database.
Patients were divided into groups by parathyroid gland remaining in situ fraction (PGRIF) (PGRIF = number of in situ glands/(total number of identified glands − number of glands in specimen).
Patients were graded by tertiles and followed at least one year after surgery.
Results.
559 patients were included.
PGRIF is significantly inversely associated with transient hypoparathyroidism, protracted hypoparathyroidism, and postoperative hypocalcemia.
PGRIF was identified as an independent risk factor for transient hypoparathyroidism, protracted hypoparathyroidism, and postoperative hypocalcemia (OR=0.177, 0.190, and 0.330, resp.).
Autotransplantation of parathyroid gland would not affect the calcium level in the long term.
Conclusion.
In situ preservation of parathyroid gland is crucial for parathyroid function.
Less preserved is the independent risk factor for postoperative hypoparathyroidism and hypocalcemia, resulting in a worse function of parathyroid gland in the long term.
American Psychological Association (APA)
Luo, Han& Zhao, Wanjun& Yang, Hongliu& Su, Anping& Wang, Bin& Zhu, Jingqiang. 2018. In Situ Preservation Fraction of Parathyroid Gland in Thyroidectomy: A Cohort Retrospective Study. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171959
Modern Language Association (MLA)
Luo, Han…[et al.]. In Situ Preservation Fraction of Parathyroid Gland in Thyroidectomy: A Cohort Retrospective Study. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171959
American Medical Association (AMA)
Luo, Han& Zhao, Wanjun& Yang, Hongliu& Su, Anping& Wang, Bin& Zhu, Jingqiang. In Situ Preservation Fraction of Parathyroid Gland in Thyroidectomy: A Cohort Retrospective Study. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171959
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171959