Advances in Chemical Synthesis of Fondaparinux

Joint Authors

Ding, Yili
Vara Prasad, Chamakura V. N. S.
Wang, Bingyun

Source

Journal of Chemistry

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-17, 17 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-05-12

Country of Publication

Egypt

No. of Pages

17

Main Subjects

Chemistry

Abstract EN

Fondaparinux (trade name Arixtra) is a safe and efficacious anticoagulant, and it is chemically related to low-molecular-weight heparins such as enoxaparin.

Fondaparinux is a synthetic pentasaccharide, and its synthesis is difficult and expensive.

The high cost of fondaparinux thwarts its extensive worldwide usage.

Over the last two decades, several research groups and pharmaceutical companies have been interested in finding efficient and practical methods for its synthesis.

The present review discusses those strategies and their pros and cons in a comparative account.

American Psychological Association (APA)

Ding, Yili& Vara Prasad, Chamakura V. N. S.& Wang, Bingyun. 2019. Advances in Chemical Synthesis of Fondaparinux. Journal of Chemistry،Vol. 2019, no. 2019, pp.1-17.
https://search.emarefa.net/detail/BIM-1172070

Modern Language Association (MLA)

Ding, Yili…[et al.]. Advances in Chemical Synthesis of Fondaparinux. Journal of Chemistry No. 2019 (2019), pp.1-17.
https://search.emarefa.net/detail/BIM-1172070

American Medical Association (AMA)

Ding, Yili& Vara Prasad, Chamakura V. N. S.& Wang, Bingyun. Advances in Chemical Synthesis of Fondaparinux. Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-17.
https://search.emarefa.net/detail/BIM-1172070

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1172070