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Retrospective Descriptive Analysis of West Nile Neuroinvasive Disease (WNND) in Northwest Louisiana
Joint Authors
Joel Chandranesan, Andrew Stevenson
Mada, Pradeep Kumar
Castano, Gabriel
Moore, Maureen
Sneed, Philip
Source
International Journal of Microbiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Context.
West Nile virus (WNV) has become endemic in many states in the United States in recent years.
One in 150 individuals with West Nile virus infection develops the West Nile neuroinvasive disease (WNND) and can cause permanent and sometimes fatal neurological damage.
Aims.
The aim of the study was to describe the presentation characteristics and epidemiology of WNND in Louisiana to improve future recognition of cases and decrease inappropriate antibiotic use.
Settings and Design.
It was a retrospective descriptive-analytic cohort study.
A total of 23 patients with WNND were identified at one tertiary care hospital center in Northwest Louisiana from a retrospective chart review from January 1, 2012 to October 31, 2017.
Results.
The median age was 49 years (range: 15–75) for patients with WNND.
Of 23 patients diagnosed with WNND, twelve (52%) were diagnosed with encephalitis (WNE), six (26%) were diagnosed with meningitis (WNM), and five (22%) with myelitis (WNME).
The common symptoms with WNND were fever in 65%, altered mental status in 61%, headache in 52%, fatigue in 43%, gastrointestinal symptoms in 43%, rigors in 30%, imbalance in 26%, rash in 9%, and seizures in 26% of patients.
Most patients presented in the late summer season.
The average duration of antibiotics given was six days.
The average number of days from the admission to the diagnosis of WNND was nine days (3 to 16 days).
Twenty-one (91%) patients survived the infection.
Conclusions.
Identifying WNV infection early in its clinical course would help in decreasing inappropriate antibiotic use when patients presented with fever and meningeal symptoms.
Performing WNV serology in CSF studies is critical in making the diagnosis.
American Psychological Association (APA)
Mada, Pradeep Kumar& Sneed, Philip& Castano, Gabriel& Moore, Maureen& Joel Chandranesan, Andrew Stevenson. 2020. Retrospective Descriptive Analysis of West Nile Neuroinvasive Disease (WNND) in Northwest Louisiana. International Journal of Microbiology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1172089
Modern Language Association (MLA)
Mada, Pradeep Kumar…[et al.]. Retrospective Descriptive Analysis of West Nile Neuroinvasive Disease (WNND) in Northwest Louisiana. International Journal of Microbiology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1172089
American Medical Association (AMA)
Mada, Pradeep Kumar& Sneed, Philip& Castano, Gabriel& Moore, Maureen& Joel Chandranesan, Andrew Stevenson. Retrospective Descriptive Analysis of West Nile Neuroinvasive Disease (WNND) in Northwest Louisiana. International Journal of Microbiology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1172089
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172089