Metabolic Syndrome and Its Components in Young Adults Conceived by ICSI
Joint Authors
Tournaye, Herman
Bonduelle, Maryse
Roelants, M.
De Schepper, J.
Belva, F.
Provyn, S.
Painter, R. C.
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Intracytoplasmic sperm injection (ICSI) conception presents the early embryo with a radically different environment, which may lead to permanent alterations to key cardiometabolic processes.
Blood pressure, indicators of insulin resistance, and lipid profiles have previously been studied in offspring born after in vitro fertilisation (IVF) and ICSI, with conflicting findings.
Also, results in young adults born after ICSI are lacking.
Aim.
We investigated if young adult men and women conceived by ICSI more frequently have metabolic syndrome and its individual features in comparison to spontaneously conceived controls.
Design.
Cardiometabolic and anthropometric parameters from 126 longitudinally followed young adults conceived by ICSI were compared to those of 133 controls.
Results.
At age 18 years, only 1 of the participants displayed the metabolic syndrome (1 control woman).
Mean concentrations of total cholesterol, triglycerides, insulin, HOMA-IR, and blood pressure were comparable between the ICSI conceived and control participants.
A higher proportion (19.6%) of men conceived by ICSI had low (<40 mg/dl) HDL cholesterol compared to controls (5.6%).
Conclusions.
While men conceived by ICSI, but not women, had lower mean HDL cholesterol concentrations in comparison to controls, other markers of the metabolic syndrome were not affected by the mode of conception.
American Psychological Association (APA)
Belva, F.& Bonduelle, Maryse& Provyn, S.& Painter, R. C.& Tournaye, Herman& Roelants, M.…[et al.]. 2018. Metabolic Syndrome and Its Components in Young Adults Conceived by ICSI. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1172118
Modern Language Association (MLA)
Belva, F.…[et al.]. Metabolic Syndrome and Its Components in Young Adults Conceived by ICSI. International Journal of Endocrinology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1172118
American Medical Association (AMA)
Belva, F.& Bonduelle, Maryse& Provyn, S.& Painter, R. C.& Tournaye, Herman& Roelants, M.…[et al.]. Metabolic Syndrome and Its Components in Young Adults Conceived by ICSI. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1172118
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172118