![](/images/graphics-bg.png)
An Efficient K2CO3-Promoted Synthesis of 1-Bromo-2-aryloxyethane Derivatives and Evaluation of Larval Mortality against Aedes aegypti
Joint Authors
Pájaro, Yina
Sathicq, Ángel
Puello-Polo, Esneyder
Pérez, Astrid
Trilleras, Jorge
Romanelli, Gustavo P.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The influences of reaction parameters on the etherification of phenols to obtain 1-bromo-2-aryloxyethane derivatives were evaluated.
The compounds were prepared by direct etherification of phenols with 1,2-dibromoethane using anhydrous K2CO3 and acetonitrile as solvent reaction, at 80°C, in a reaction time of 6 h.
Under these conditions, excellent yields (71%–94%) were obtained, with low yields of secondary products.
The anhydrous K2CO3 was recycled by simple filtration, dried in vacuum, and reused.
The compounds were characterized by conventional spectral data (MS and NMR).
Larvicidal activity results showed a 100% larval mortality after 24-hour exposure to the compound 1-(2-bromoethoxy)-2-phenylbenzene.
American Psychological Association (APA)
Pájaro, Yina& Sathicq, Ángel& Puello-Polo, Esneyder& Pérez, Astrid& Romanelli, Gustavo P.& Trilleras, Jorge. 2017. An Efficient K2CO3-Promoted Synthesis of 1-Bromo-2-aryloxyethane Derivatives and Evaluation of Larval Mortality against Aedes aegypti. Journal of Chemistry،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1172127
Modern Language Association (MLA)
Pájaro, Yina…[et al.]. An Efficient K2CO3-Promoted Synthesis of 1-Bromo-2-aryloxyethane Derivatives and Evaluation of Larval Mortality against Aedes aegypti. Journal of Chemistry No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1172127
American Medical Association (AMA)
Pájaro, Yina& Sathicq, Ángel& Puello-Polo, Esneyder& Pérez, Astrid& Romanelli, Gustavo P.& Trilleras, Jorge. An Efficient K2CO3-Promoted Synthesis of 1-Bromo-2-aryloxyethane Derivatives and Evaluation of Larval Mortality against Aedes aegypti. Journal of Chemistry. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1172127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172127