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TriglyceridesGlucose and TriglycerideHigh-Density Lipoprotein Cholesterol Indices in Normal and Preeclamptic Pregnancies: A Longitudinal Study
Joint Authors
Poveda, Natalia Elvira
Garcés, María Fernanda
Darghan, Aquiles Enrique
Jaimes, Silvia Alejandra Blanco
Sánchez, Estefania Pulido
Díaz-Cruz, Luz Amparo
Garzón-Olivares, Carmen Doris
Parra-Pineda, Mario Orlando
Bautista-Charry, Alejandro Antonio
Müller, Edith Ángel
Alzate, Héctor Fabio Sandoval
Acosta, Luis Miguel Maldonado
Sanchez, Elizabeth
Ruíz-Parra, Ariel Iván
Caminos, Jorge E.
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Metabolic changes have been correlated with adverse pregnancy outcomes.
The aim of the present study is to determine the TyG and TG/HDL-c indices in a cohort of healthy pregnant (n=142), preeclamptic (n=18), and healthy nonpregnant women (n=56).
Preeclamptic women were selected from the same cohort.
Pregnant women were followed during three periods of pregnancy and postpartum.
The results showed a significant increase in the values of TyG and TG/HDL-c (p<0.01) as pregnancy progresses, without significant differences between healthy and preeclamptic women.
TyG and TG/HDL-c indices are significantly low in nonpregnant and three months’ postpartum women when compared with each gestational period studied.
TyG and TG/HDL-c indices are positively correlated with HOMA-IR in the early and middle pregnancy (p<0.05).
Multiple linear regression using the TyG and TG/HDL-c indices as dependent variables showed that TyG index was significantly associated with HOMA-IR, gestational age, HDL-c, TC, LDL, fasting insulin, and mean BP (p<0.001); meanwhile, TG/HDL-c index was only associated with HOMA-IR (p<0.0242) and gestational age (p<0.001).
In conclusion, the TyG and TG/HDL-c indices could be useful in monitoring insulin resistance during pregnancy.
American Psychological Association (APA)
Poveda, Natalia Elvira& Garcés, María Fernanda& Darghan, Aquiles Enrique& Jaimes, Silvia Alejandra Blanco& Sánchez, Estefania Pulido& Díaz-Cruz, Luz Amparo…[et al.]. 2018. TriglyceridesGlucose and TriglycerideHigh-Density Lipoprotein Cholesterol Indices in Normal and Preeclamptic Pregnancies: A Longitudinal Study. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1172257
Modern Language Association (MLA)
Poveda, Natalia Elvira…[et al.]. TriglyceridesGlucose and TriglycerideHigh-Density Lipoprotein Cholesterol Indices in Normal and Preeclamptic Pregnancies: A Longitudinal Study. International Journal of Endocrinology No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1172257
American Medical Association (AMA)
Poveda, Natalia Elvira& Garcés, María Fernanda& Darghan, Aquiles Enrique& Jaimes, Silvia Alejandra Blanco& Sánchez, Estefania Pulido& Díaz-Cruz, Luz Amparo…[et al.]. TriglyceridesGlucose and TriglycerideHigh-Density Lipoprotein Cholesterol Indices in Normal and Preeclamptic Pregnancies: A Longitudinal Study. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1172257
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172257