The Role of the NIS (SLC5A5) Gene in Papillary Thyroid Cancer: A Systematic Review
Joint Authors
Nóbrega, Otávio Toledo
Silva, Izabel Cristina Rodrigues da
de Morais, Rafael Martins
Sobrinho, Alaor Barra
de Souza Silva, Calliandra Maria
de Oliveira, Jamila Reis
Source
International Journal of Endocrinology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-14
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Papillary thyroid cancer (PTC) is the most common thyroid malignancy.
Genetic and epigenetic alterations play a decisive role in the onset of several human neoplasms.
Mutations and polymorphisms are two frequent genetic alterations.
Located on chromosome 19 (19p13.11), the NIS SLC5A5 (solute carrier family 5 member 5) gene encodes a highly specialized and efficient 80–90 kDa transmembrane glycoprotein that mediates active transport of iodide from the bloodstream into the follicular cells.
Given the highly significant role of NIS in the physiology and the cancer pathogenesis process, this paper’s objective is to provide a comprehensive assessment of the associations between NIS gene and protein with papillary thyroid cancer.
American Psychological Association (APA)
de Morais, Rafael Martins& Sobrinho, Alaor Barra& de Souza Silva, Calliandra Maria& de Oliveira, Jamila Reis& Silva, Izabel Cristina Rodrigues da& Nóbrega, Otávio Toledo. 2018. The Role of the NIS (SLC5A5) Gene in Papillary Thyroid Cancer: A Systematic Review. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1172294
Modern Language Association (MLA)
de Morais, Rafael Martins…[et al.]. The Role of the NIS (SLC5A5) Gene in Papillary Thyroid Cancer: A Systematic Review. International Journal of Endocrinology No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1172294
American Medical Association (AMA)
de Morais, Rafael Martins& Sobrinho, Alaor Barra& de Souza Silva, Calliandra Maria& de Oliveira, Jamila Reis& Silva, Izabel Cristina Rodrigues da& Nóbrega, Otávio Toledo. The Role of the NIS (SLC5A5) Gene in Papillary Thyroid Cancer: A Systematic Review. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1172294
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172294
