Antibacterial Potential of Jatropha sp. Latex against Multidrug-Resistant Bacteria
Joint Authors
Prastiyanto, Muhammad Evy
Tama, Prayoda Deri
Ananda, Ninda
Wilson, Wildiani
Mukaromah, Ana Hidayati
Source
International Journal of Microbiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
This study was aimed to evaluate the antibacterial activity of the latex of three species members of Jatropha (J.
curcas, J.
gossypilofia Linn., and J.
multifida) against methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum beta-lactamase- (ESBL-) producing Escherichia coli and ESBL-producing Klebsiella pneumonia, carbapenemase-resistant Enterobacteriaceae (CRE)-E.
coli, K.
pneumoniae-carbapenemase (KPC), and carbapenemase-resistant Pseudomonas aeruginosa (CRPA).
Method.
The antibacterial activities were calculated based on the inhibition zones using the Mueller–Hinton agar diffusion method, minimum inhibitory concentration (MIC) using Mueller–Hinton broth in a microdilution method, and minimum bactericidal concentration (MBC) using blood agar plate.
Results.
The latex of Jatropha showed antibacterial activities against the MRSA and CRPA.
All latex of Jatropha appeared to have the antibacterial activities against MRSA and CRPA in the diffusion method (20.4–23.7 mm and 12–15 mm), MIC (0.19–6.25%, and 25%), and MBC (0.39–12.5% and 50%).
Phytochemical screening of latex indicated the presence of flavonoids.
Conclusions.
The latex of J.
curcas, J.
gossypilofia Linn., and J.
multifida has the potential to be developed as antibacterial agents, especially against MRSA and CRPA strain, but further in vivo research and discovery of the mode of its action are required to shed the light on the effects.
American Psychological Association (APA)
Prastiyanto, Muhammad Evy& Tama, Prayoda Deri& Ananda, Ninda& Wilson, Wildiani& Mukaromah, Ana Hidayati. 2020. Antibacterial Potential of Jatropha sp. Latex against Multidrug-Resistant Bacteria. International Journal of Microbiology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1172307
Modern Language Association (MLA)
Prastiyanto, Muhammad Evy…[et al.]. Antibacterial Potential of Jatropha sp. Latex against Multidrug-Resistant Bacteria. International Journal of Microbiology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1172307
American Medical Association (AMA)
Prastiyanto, Muhammad Evy& Tama, Prayoda Deri& Ananda, Ninda& Wilson, Wildiani& Mukaromah, Ana Hidayati. Antibacterial Potential of Jatropha sp. Latex against Multidrug-Resistant Bacteria. International Journal of Microbiology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1172307
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172307