Immunoinformatic Analysis to Identify Proteins to Be Used as Potential Targets to Control Bovine Anaplasmosis
Joint Authors
Martínez-Ocampo, Fernando
Amaro-Estrada, Itzel
Aguilar-Díaz, Hugo
Rodríguez-Camarillo, Sergio D.
Quiroz-Castañeda, Rosa E.
Vara-Pastrana, José E.
Pescador-Pérez, Diego
Source
International Journal of Microbiology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Omics sciences and new technologies to sequence full genomes provide valuable data that are revealed only after detailed bioinformatic analysis is performed.
In this work, we analyzed the genomes of seven Mexican Anaplasma marginale strains and the data from a transcriptome analysis of the tick Rhipicephalus microplus.
The aim of this analysis was to identify protein sequences with predicted features to be used as potential targets to control the bacteria or tick-vector transmission.
We chose three amino acid sequences different to all proteins previously reported in A.
marginale that have been used as potential vaccine candidates, and also, we report, for the first time, the presence of a peroxinectin protein sequence in the transcriptome of R.
microplus, a protein associated with the immune response of ticks.
The bioinformatics analyses revealed the presence of B-cell epitopes in all the amino acid sequences chosen, which opens the way for their likely use as single or arranged peptides to develop new strategies for the control and prevention of bovine anaplasmosis transmitted by ticks.
American Psychological Association (APA)
Rodríguez-Camarillo, Sergio D.& Quiroz-Castañeda, Rosa E.& Aguilar-Díaz, Hugo& Vara-Pastrana, José E.& Pescador-Pérez, Diego& Amaro-Estrada, Itzel…[et al.]. 2020. Immunoinformatic Analysis to Identify Proteins to Be Used as Potential Targets to Control Bovine Anaplasmosis. International Journal of Microbiology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1172490
Modern Language Association (MLA)
Rodríguez-Camarillo, Sergio D.…[et al.]. Immunoinformatic Analysis to Identify Proteins to Be Used as Potential Targets to Control Bovine Anaplasmosis. International Journal of Microbiology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1172490
American Medical Association (AMA)
Rodríguez-Camarillo, Sergio D.& Quiroz-Castañeda, Rosa E.& Aguilar-Díaz, Hugo& Vara-Pastrana, José E.& Pescador-Pérez, Diego& Amaro-Estrada, Itzel…[et al.]. Immunoinformatic Analysis to Identify Proteins to Be Used as Potential Targets to Control Bovine Anaplasmosis. International Journal of Microbiology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1172490
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172490