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Optimal Control Strategies for the Infectiology of Brucellosis
Joint Authors
Mpeshe, Saul C.
Luboobi, Livingstone
Shirima, Gabriel M.
Nyerere, Nkuba
Source
International Journal of Mathematics and Mathematical Sciences
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-11
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Brucellosis is a zoonotic infection caused by Gram-negative bacteria of genus Brucella.
The disease is of public health, veterinary, and economic significance in most of the developed and developing countries.
Direct contact between susceptible and infective animals or their contaminated products are the two major routes of the disease transmission.
In this paper, we investigate the impacts of controls of livestock vaccination, gradual culling through slaughter of seropositive cattle and small ruminants, environmental hygiene and sanitation, and personal protection in humans on the transmission dynamics of Brucellosis.
The necessary conditions for an optimal control problem are rigorously analyzed using Pontryagin’s maximum principle.
The main ambition is to minimize the spread of brucellosis disease in the community as well as the costs of control strategies.
Findings showed that the effective use of livestock vaccination, gradual culling through slaughter of seropositive cattle and small ruminants, environmental hygiene and sanitation, and personal protection in humans have a significant impact in minimizing the disease spread in livestock and human populations.
Moreover, cost-effectiveness analysis of the controls showed that the combination of livestock vaccination, gradual culling through slaughter, environmental sanitation, and personal protection in humans has high impact and lower cost of prevention.
American Psychological Association (APA)
Nyerere, Nkuba& Luboobi, Livingstone& Mpeshe, Saul C.& Shirima, Gabriel M.. 2020. Optimal Control Strategies for the Infectiology of Brucellosis. International Journal of Mathematics and Mathematical Sciences،Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1172588
Modern Language Association (MLA)
Nyerere, Nkuba…[et al.]. Optimal Control Strategies for the Infectiology of Brucellosis. International Journal of Mathematics and Mathematical Sciences No. 2020 (2020), pp.1-17.
https://search.emarefa.net/detail/BIM-1172588
American Medical Association (AMA)
Nyerere, Nkuba& Luboobi, Livingstone& Mpeshe, Saul C.& Shirima, Gabriel M.. Optimal Control Strategies for the Infectiology of Brucellosis. International Journal of Mathematics and Mathematical Sciences. 2020. Vol. 2020, no. 2020, pp.1-17.
https://search.emarefa.net/detail/BIM-1172588
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172588