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Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate of Pantoea vagans PV989
Joint Authors
Bao, Qiyu
Lin, Chaoqing
Liu, Yabo
Lu, Junwan
Lu, Shunfei
Ying, Yuanyuan
Xu, Teng
Ying, Jianchao
Xu, Lei
Yin, Min
Zhu, Tingyuan
Ni, Liyan
Source
International Journal of Genomics
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Pantoea vagans, a gram-negative bacterium from the genus Pantoea and family Enterobacteriaceae, is present in various natural environments and considered to be plant endophytes.
We isolated the Pantoea vagans PV989 strain from the clinic and sequenced its whole genome.
Besides a chromosome DNA molecule, it also harboured three large plasmids.
A comparative genomics analysis was performed for the smallest plasmid, pPV989-94.
It can be divided into four regions, including three conservative regions related to replication (R1), transfer conjugation (R2), and transfer leading (R3), and one variable region (R4).
Further analysis showed that pPV989-94 is most similar to plasmids LA637P2 and pEA68 of Erwinia amylovora strains isolated from fruit trees.
These three plasmids share three conservative regions (R1, R2, and R3).
Interestingly, a fragment (R4′) in R4, mediated by phage integrase and phage integrase family site-specific recombinase and encoding 9 genes related to glycometabolism, resistance, and DNA repair, was unique in pPV989-94.
Homologues of R4′ were found in other plasmids or chromosomes, suggesting that horizontal gene transfer (HGT) occurred among different bacteria of various species or genera.
The acquired functional genes may play important roles in the adaptation of bacteria to different hosts or environmental conditions.
American Psychological Association (APA)
Xu, Lei& Yin, Min& Zhu, Tingyuan& Liu, Yabo& Ying, Yuanyuan& Lu, Junwan…[et al.]. 2018. Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate of Pantoea vagans PV989. International Journal of Genomics،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1172662
Modern Language Association (MLA)
Xu, Lei…[et al.]. Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate of Pantoea vagans PV989. International Journal of Genomics No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1172662
American Medical Association (AMA)
Xu, Lei& Yin, Min& Zhu, Tingyuan& Liu, Yabo& Ying, Yuanyuan& Lu, Junwan…[et al.]. Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate of Pantoea vagans PV989. International Journal of Genomics. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1172662
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172662